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Literature summary for 1.13.11.12 extracted from
- Identification of an amino acid determinant of pH regiospecificity in a seed lipoxygenase from Momordica charantia (2008), Phytochemistry, 69, 2774-2780.
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| Q599H | converts the enzyme to a pure 13-LOX | Momordica charantia |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Momordica charantia | B7FDE5 | - |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| seed | - |
Momordica charantia | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| linoleic acid + O2 | - |
Momordica charantia | (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoic acid | at pH-values higher than 7.5 the enzyme constitutes a linoleate 13-LOX whereas at lower pH, 9-H(P)ODE is the major reaction product. Glutamine 599 plays a role in pH-dependence of the reaction specificity | ? |  |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| LOX | - |
Momordica charantia |
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Release 2023.1 (January 2023)
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