Protein Variants | Comment | Organism |
---|---|---|
additional information | deletion of lox greatly diminishes density-dependent development of both sclerotia and conidia, resulting in an overall increase in the number of sclerotia and a decrease in the number of conidia at high cell densities. Lox mutants show decreased linoleic acid LOX activity | Aspergillus flavus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Fe | the iron atom in LOX is bound by four ligands, three of which are histidine residues | Aspergillus flavus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Aspergillus flavus | B5SXD0 | strains NRRL 3357, TSHB3.1C and TSHB3.5C | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
linoleic acid + O2 | - |
Aspergillus flavus | (9Z,11E)-(13S)-13-hydroperoxyoctadeca-9,11-dienoic acid | - |
? |
Synonyms | Comment | Organism |
---|---|---|
LOX | - |
Aspergillus flavus |
Organism | Comment | Expression |
---|---|---|
Aspergillus flavus | Lox is a low-expression gene, no expression in wild-type strain NRRL 3357 | down |
Aspergillus flavus | Lox is expressed in the complemented strains TSHB3.1C and TSHB3.5C. While complemented strain TSHB3.1C (harboring a single-copy insertion) expresses a clear transcript, complemented strain TSHB3.5C (harboring at least two copies of lox and likely more) produces a greatly increased transcript and also produces an additional smaller band, which is absent in the single-copy strain TSHB3.1C | up |
General Information | Comment | Organism |
---|---|---|
malfunction | deletion of lox greatly diminishes density-dependent development of both sclerotia and conidia, resulting in an overall increase in the number of sclerotia and a decrease in the number of conidia at high cell densities. Lox mutants show decreased linoleic acid LOX activity | Aspergillus flavus |