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Literature summary for 1.12.1.4 extracted from

  • Schut, G.J.; Adams, M.W.
    The iron-hydrogenase of Thermotoga maritima utilizes ferredoxin and NADH synergistically: a new perspective on anaerobic hydrogen production (2009), J. Bacteriol., 191, 4451-4457.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.12.1.4

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Thermotoga maritima 5737
-

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
NADH + H+ + reduced ferredoxin Thermotoga maritima the iron hydrogenase requires the presence of both electron carriers, NADH and ferredoxin, for catalysis of H2 production H2 + NAD+ + oxidized ferredoxin
-
 ?
NADH + H+ + reduced ferredoxin Thermotoga maritima DSM 3109 the iron hydrogenase requires the presence of both electron carriers, NADH and ferredoxin, for catalysis of H2 production H2 + NAD+ + oxidized ferredoxin
-
 ?

Organism

Organism UniProt Comment Textmining
Thermotoga maritima
-
-
-
Thermotoga maritima DSM 3109
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
NADH + H+ + reduced ferredoxin the iron hydrogenase requires the presence of both electron carriers, NADH and ferredoxin, for catalysis of H2 production Thermotoga maritima H2 + NAD+ + oxidized ferredoxin
-
 ?
NADH + H+ + reduced ferredoxin the iron hydrogenase requires the presence of both electron carriers, NADH and ferredoxin, for catalysis of H2 production Thermotoga maritima DSM 3109 H2 + NAD+ + oxidized ferredoxin
-
 ?
NADH + H+ + reduced methyl viologen
-
 Thermotoga maritima H2 + NAD+ + oxidized methyl viologen
-
 ?

Subunits

Subunits Comment Organism
heterotrimer
-
 Thermotoga maritima

Synonyms

Synonyms Comment Organism
bifurcating [FeFe] hydrogenase
-
 Thermotoga maritima
iron hydrogenase
-
 Thermotoga maritima
[FeFe]-type hydrogenase
-
 Thermotoga maritima

Cofactor

Cofactor Comment Organism Structure
FMN
-
 Thermotoga maritima
iron-sulfur centre the alpha subunit contains two [2Fe-2S] clusters and three [4Fe-4S] clusters, the beta subunit contains three [4Fe-4S] clusters and one [2Fe-2S] clusters, the gamma subunit contains one [2Fe-2S] cluster Thermotoga maritima