Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
phagosome | - |
Homo sapiens | - |
- |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Cl- + H2O2 + H+ | at acidic pH, chlorinating activity of MPO dominates | Homo sapiens | HClO + H2O | - |
? | |
guaiacol + H2O2 | at neutral pH MPO has higher affinity to peroxidase substrate guaiacol | Homo sapiens | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
MPO | - |
Homo sapiens |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
4.7 | 6 | optimum pH for peroxidase activity of MPO | Homo sapiens |
7.4 | - |
optimum pH for chlorinating activity of MPO, at pH 7.4 chloride ions do not compete with guaiacol up to the concentration of 150 mM | Homo sapiens |
General Information | Comment | Organism |
---|---|---|
physiological function | balance between peroxidase and chlorinating activities of myeloperoxidase is very important for the enhancement of antimicrobial action and prevention of damage caused by hypochlorite | Homo sapiens |