Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
Br- + H2O2 | at physiological concentrations of chloride and bromide, hypobromous acid can be a major oxidant produced by myeloperoxidase | Homo sapiens | HBrO + H2O | - |
? | |
Cl- + H2O2 | - |
Homo sapiens | HClO + H2O | - |
? | |
additional information | bromide, at physiological concentrations, promotes a dramatic increase in bromination of human serum albumin catalyzed by myeloperoxidase | Homo sapiens | ? | - |
? | |
thiocyanate + H2O2 | - |
Homo sapiens | hypothiocyanite + H2O | - |
? |
pH Minimum | pH Maximum | Comment | Organism |
---|---|---|---|
5 | 7.8 | between pH 5.0 and 7.0, myeloperoxidase converts about 90% of available hydrogen peroxide to hypochlorous acid and the remainder to hypobromous acid. Above pH 7, there is an abrupt rise in the yield of hypobromous acid. At pH 7.8, it accounts for 40% of the hydrogen peroxide | Homo sapiens |