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Literature summary for 1.11.1.9 extracted from
- Phospholipid hydroperoxide glutathione peroxidase plays a role in protecting cancer cells from docosahexaenoic acid-induced cytotoxicity (2007), Mol. Cancer Ther., 6, 1467-1474.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| docosahexaenoic acid | 0.1 mM reduces the level of protein expression of GPx-4 by at least 50% | Homo sapiens |  |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 20000 | - |
SDS-PAGE | Homo sapiens |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| A-2780 cell | - |
Homo sapiens | - |
| A2780/CP70 cell | - |
Homo sapiens | - |
| C-8161 cell | - |
Homo sapiens | - |
| CEM cell | - |
Homo sapiens | - |
| HL-60 cell | - |
Homo sapiens | - |
| MM1.R cell | - |
Homo sapiens | - |
| MM1.S cell | - |
Homo sapiens | - |
| RAJI cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| H2O2 + GSH | - |
Homo sapiens | H2O + GSSG | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| GPx-4 | - |
Homo sapiens |
| phospholipid hydroperoxide glutathione peroxidase | - |
Homo sapiens |
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Release 2023.1 (January 2023)
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