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Literature summary for 1.11.1.9 extracted from
- Purification and properties of rat lung soluble glutathione peroxidase (1976), Biochim. Biophys. Acta, 445, 558-566.
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| cytosol | - |
Rattus norvegicus | 5829 | - |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 75000 | 85500 | gel filtration | Rattus norvegicus |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + ROOH | Rattus norvegicus | lauryl hydroperoxide | glutathione disulfide + ROH + H2O | - |
? |  |
| glutathione + ROOH | Rattus norvegicus | cumene hydroperoxide | glutathione disulfide + ROH + H2O | - |
? | |
| glutathione + ROOH | Rattus norvegicus | dithiothreitol has 10% of glutathione activity | glutathione disulfide + ROH + H2O | - |
? | |
| glutathione + ROOH | Rattus norvegicus | highly specific for glutathione | glutathione disulfide + ROH + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Rattus norvegicus | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Rattus norvegicus |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| lung | - |
Rattus norvegicus | - |
Storage Stability
| Storage Stability | Organism |
|---|---|
| 4°C, 1 month, less than 50% loss of activity | Rattus norvegicus |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| glutathione + ROOH | lauryl hydroperoxide | Rattus norvegicus | glutathione disulfide + ROH + H2O | - |
? | |
| glutathione + ROOH | cumene hydroperoxide | Rattus norvegicus | glutathione disulfide + ROH + H2O | - |
? | |
| glutathione + ROOH | dithiothreitol has 10% of glutathione activity | Rattus norvegicus | glutathione disulfide + ROH + H2O | - |
? | |
| glutathione + ROOH | highly specific for glutathione | Rattus norvegicus | glutathione disulfide + ROH + H2O | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| homotetramer | alpha4, 4 * 17000-20000, SDS-PAGE, amino acid composition | Rattus norvegicus |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 8.8 | 9 | - |
Rattus norvegicus |
pH Range
| pH Minimum | pH Maximum | Comment | Organism |
|---|---|---|---|
| 7 | - |
less than 20% of maximal activity below | Rattus norvegicus |
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Release 2023.1 (January 2023)
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