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Literature summary for 1.11.1.8 extracted from

  • Godlewska, M.; Krasuska, W.; Czarnocka, B.
    Biochemical properties of thyroid peroxidase (TPO) expressed in human breast and mammary-derived cell lines (2018), PLoS ONE, 13, e0193624 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.11.1.8

Localization

Localization Comment Organism GeneOntology No. Textmining
cytoplasm
-
 Homo sapiens 5737
-

Organism

Organism UniProt Comment Textmining
Homo sapiens P07202
-
-

Posttranslational Modification

Posttranslational Modification Comment Organism
glycoprotein the content of asparagine-linked carbohydrates in breast tissue TPO (3 kDA) is lower than in thyroid TPO (at least 10 kDa) Homo sapiens

Source Tissue

Source Tissue Comment Organism Textmining
184A1 cell
-
 Homo sapiens
-
breast the molecular weight of breast TPO is slightly lower than that of thyroid TPO due to decreased glycosylation. Enzymatic activity and isoelectric point of the isomforms are comparable Homo sapiens
-
MCF-7 cell
-
 Homo sapiens
-
MDA-MB-231 cell
-
 Homo sapiens
-
thyroid gland the molecular weight of breast TPO is slightly lower than that of thyroid TPO due to decreased glycosylation. Enzymatic activity and isoelectric point of the isomforms are comparable Homo sapiens
-

Subunits

Subunits Comment Organism
? x * 100000, SDS-PAGE, thyroid isoform Homo sapiens
? x * 94000, SDS-PAGE, breast tissue isoform Homo sapiens

Synonyms

Synonyms Comment Organism
TPO
-
 Homo sapiens

pI Value

Organism Comment pI Value Maximum pI Value
Homo sapiens and 7.1, isoelectric focusing, breast tissue isoform
-
 6.4
Homo sapiens and 6.4, isoelectric focusing, breast tissue isoform
-
 7.1