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Literature summary for 1.11.1.8 extracted from

  • Rebuffat, S.A.; Bresson, D.; Nguyen, B.; Peraldi-Roux, S.
    The key residues in the immunodominant region 353-363 of human thyroid peroxidase were identified (2006), Int. Immunol., 18, 1091-1099.
    View publication on PubMed
Search for more literature for 1.11.1.8

Cloned(Commentary)

Cloned (Comment) Organism
stable expression of mutant enzymes at the surface of CHO cells Homo sapiens

Protein Variants

Protein Variants Comment Organism
D358A mutation at position 358 led to a loss of the binding of human anti-TPO autoantibodies as efficient as a mutation of the entire region 353–363 Homo sapiens
additional information H353, D358, S359 and R361 are amino acid residues contributing to the binding of anti-TPO autoantibodies in the immunodominant regions Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens
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-
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Source Tissue

Source Tissue Comment Organism Textmining
thyroid gland
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 Homo sapiens
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Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
additional information H353, D358, S359 and R361 are amino acid residues contributing to the binding of anti-TPO autoantibodies in the immunodominant regions Homo sapiens ?
-
 ?