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Literature summary for 1.11.1.8 extracted from
- Characterization of hog thyroid peroxidase (1985), J. Biol. Chem., 260, 441-448.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| Aminotriazole | very strong | Sus scrofa |  |
| azide | non competitive with H2O2 | Sus scrofa | |
| cyanide | competitive with H2O2 | Sus scrofa | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 71000 | - |
HPLC gel filtration | Sus scrofa |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| iodide + H2O2 | Sus scrofa | - |
iodine + H2O | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Sus scrofa | - |
pig, female | - |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| diiodotyrosine + H2O2 + I- | - |
Sus scrofa | ? | - |
? | |
| guaiacol + H2O2 + I- | - |
Sus scrofa | tetraguaiacol + H2O | - |
? | |
| iodide + H2O2 | - |
Sus scrofa | iodine + H2O | - |
? | |
| tyrosine + H2O2 + I- | - |
Sus scrofa | monoiodotyrosine + diiodotyrosine + H2O | - |
? | |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| protoheme | - |
Sus scrofa | |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.001 | 0.008 | azide | depending on substrate | Sus scrofa | |
| 0.009 | - |
cyanide | - |
Sus scrofa | |
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