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Literature summary for 1.11.1.7 extracted from
- Heme peroxidase-catalyzed iodination of human angiotensins and the effect of iodination on angiotensin converting enzyme activity (2008), Inorg. Chem., 47, 6569-6571.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 5-methyl-2-thiouracil | - |
Bos taurus |  |
| 5-n-propyl-2-thiouracil | - |
Bos taurus | |
| captopril | - |
Bos taurus | |
| I3- | - |
Bos taurus | |
| Methimazole | - |
Bos taurus | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Bos taurus | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | lactoperoxidase can effectively and selectively iodinate the tyrosyl residues in angiotensin peptides | Bos taurus | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| heme peroxidase | - |
Bos taurus |
| lactoperoxidase | - |
Bos taurus |
| LPO | - |
Bos taurus |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.00274 | - |
- |
Bos taurus | Methimazole | |
| 0.00576 | - |
- |
Bos taurus | 5-methyl-2-thiouracil | |
| 0.00885 | - |
- |
Bos taurus | 5-n-propyl-2-thiouracil | |
| 0.00951 | - |
- |
Bos taurus | captopril | |
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Release 2023.1 (January 2023)
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