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Literature summary for 1.11.1.7 extracted from
- Peroxidase from human cervical mucus. The isolation and characterisation (1976), Eur. J. Biochem., 65, 325-331.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| 1,10-phenanthroline | 69% inhibition at 5 mM | Homo sapiens |  |
| 2,2'-bipyridyl | 25% inhibition at 5 mM | Homo sapiens | |
| diethyldithiocarbamate | 87% inhibition at 1 mM | Homo sapiens | |
| ethylene diamine tetraacetic acid | 17% inhibition at 10 mM | Homo sapiens | |
| hydroxylamine | 84% inhibition at 1 mM | Homo sapiens | |
| N-ethylmaleimide | 18% inhibition at 5 mM | Homo sapiens | |
| NaCN | 0.5 mM, 93% inhibition | Homo sapiens | |
| NaN3 | 99% inhibition at 20 mM | Homo sapiens | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.21 | - |
2,2'-azino-bis(3-ethylbenzthiazole-6-sulfonic acid) | - |
Homo sapiens | |
| 0.48 | - |
o-Dianisidine | - |
Homo sapiens | |
| 10.5 | - |
guaiacol | - |
Homo sapiens | |
| 23.8 | - |
pyrogallol | - |
Homo sapiens | |
| 83.33 | - |
4-aminophenazone | - |
Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| cervical mucus | - |
Homo sapiens | - |
Specific Activity [micromol/min/mg]
| Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
|---|---|---|---|
| 2.05 | - |
with 2,2'-azino-bis(3-ethylbenzthiazole-6-sulfonic acid) | Homo sapiens |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2,2'-azino-bis(3-ethylbenzthiazole-6-sulfonic acid) + H2O2 | - |
Homo sapiens | ? | - |
? | |
| 4-aminophenazone + H2O2 | - |
Homo sapiens | ? | - |
r | |
| guaiacol + H2O2 | - |
Homo sapiens | tetraguaiacol + H2O | - |
? | |
| o-dianisidine + H2O2 | - |
Homo sapiens | ? | - |
? | |
| pyrogallol + H2O2 | - |
Homo sapiens | purpurogallin + H2O | - |
? | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 4.5 | - |
oxidation of 2,2'-azino-bis(3-ethylbenzthiazole-6-sulfonic acid) | Homo sapiens |
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