Cloned (Comment) | Organism |
---|---|
DNA and amino acid sequence determination and analysis, phylogenetic analyis | Eriocheir sinensis |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
peroxisome | - |
Eriocheir sinensis | 5777 | - |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
58860 | - |
4x * 58860, sequence calculation | Eriocheir sinensis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 H2O2 | Eriocheir sinensis | - |
O2 + 2 H2O | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Eriocheir sinensis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
gill | - |
Eriocheir sinensis | - |
gonad | - |
Eriocheir sinensis | - |
heart | - |
Eriocheir sinensis | - |
hemocyte | - |
Eriocheir sinensis | - |
hepatopancreas | high expression level | Eriocheir sinensis | - |
additional information | constitutive epression, tissue expression analysis, overview | Eriocheir sinensis | - |
muscle | - |
Eriocheir sinensis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
2 H2O2 | - |
Eriocheir sinensis | O2 + 2 H2O | - |
? |
Subunits | Comment | Organism |
---|---|---|
homotetramer | 4x * 58860, sequence calculation | Eriocheir sinensis |
Synonyms | Comment | Organism |
---|---|---|
CAT | - |
Eriocheir sinensis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
heme | EsCAT contains a proximal heme-ligand signature motif, 350RLFSYNDTH358. Each monomer contains a single heme | Eriocheir sinensis | |
NADPH | Each monomer contains a NADPH bound on the surface of each monomer by 12 amino acid residues and protects the enzyme from oxidation by its substrate, H2O2 | Eriocheir sinensis |
Organism | Comment | pI Value Maximum | pI Value |
---|---|---|---|
Eriocheir sinensis | sequence calculation | - |
6.9 |
General Information | Comment | Organism |
---|---|---|
evolution | EsCAT contains a highly conserved proximal active-site signature motif (60FDRERIPERVVHAKGAL76) and a proximal heme-ligand signature motif (350RLFSYNDTH358) and exhibits high similarity with other reported CATs | Eriocheir sinensis |
physiological function | catalase is an antioxidant enzyme and plays a significant role in the protection against oxidative stress by reducing hydrogen peroxide | Eriocheir sinensis |