Protein Variants | Comment | Organism |
---|---|---|
S315T | mutation at katG codon 315 detected in 17 (63.0%) of the 27 isoniazid-resistant isolates analyzed. The most prevalent mutation observed is AGC315ACC (Ser315Thr), involving 11(65%) of the 17 isoniazid-resistant isolates having a mutation in the sequenced region. Ten isoniazid-resistant and all 29 isoniazid-susceptible isolates sequenced have no mutation in this region. Of the 19 multi-drug-resistant isolates, 15 (78.9%) show a mutation in codon 315, while only two (25%) of the eight isoniazid mono-resistant isolates are found to have a mutation in that codon | Mycobacterium tuberculosis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mycobacterium tuberculosis | - |
clinical isolates from Malatya, Turkey | - |