Literature summary for 1.11.1.24 extracted from

Liao, J.; Wang, K.; Yao, W.; Yi, X.; Yan, H.; Chen, M.; Lan, X.
Cloning, expression and antioxidant activity of a thioredoxin peroxidase from Branchiostoma belcheri tsingtaunese (2017), PLoS ONE, 12, e0175162 .

Search for more literature for 1.11.1.24

Cloned(Commentary)

Cloned (Comment)	Organism
expressed with a polyhistidine-tag in Escherichia coli	Branchiostoma belcheri tsingtauense

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
cytoplasm	-	Branchiostoma belcheri tsingtauense	5737	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
22150	-	calculated from sequence	Branchiostoma belcheri tsingtauense
24000	-	SDS-PAGE	Branchiostoma belcheri tsingtauense

Organism

Organism	UniProt	Comment	Textmining
Branchiostoma belcheri tsingtauense	Q5XUI0	-	-

Purification (Commentary)

Purification (Comment)	Organism
-	Branchiostoma belcheri tsingtauense

Source Tissue

Source Tissue	Comment	Organism	Textmining
gastrula	TPx1 is expressed in all developmental stages, with the highest level in gastrula	Branchiostoma belcheri tsingtauense	-
gill	the enzyme is expressed in all adult amphioxus tissues except testis, with the highest level found in the gill	Branchiostoma belcheri tsingtauense	-
ovary	high expression	Branchiostoma belcheri tsingtauense	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
H2O2 + dithiothreitol	no activity with glutathione	Branchiostoma belcheri tsingtauense	H2O + oxidized dithiothreitol	-	?

Subunits

Subunits	Comment	Organism
dimer	2 * 24000, existed as a dimer under non-reducing conditions, and is dissociated into monomers by dithiothreitol. It might predominantly exist in oligomeric form, SDS-PAGE	Branchiostoma belcheri tsingtauense

Synonyms

Synonyms	Comment	Organism
TPx1	-	Branchiostoma belcheri tsingtauense

pI Value

Organism	Comment	pI Value Maximum	pI Value
Branchiostoma belcheri tsingtauense	calculated from sequence	-	7.3

General Information

General Information	Comment	Organism
physiological function	the enzyme plays an antioxidant role in vivo and helps cells survive the oxidative stress. It might participate in innate immunity	Branchiostoma belcheri tsingtauense

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Release 2023.1 (January 2023)