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Literature summary for 1.11.1.24 extracted from
- Helminth 2-Cys peroxiredoxin drives Th2 responses through a mechanism involving alternatively activated macrophages (2008), FASEB J., 22, 4022-4032.
Cloned(Commentary)
| Cloned (Comment) | Organism |
|---|---|
| expressed in Escherichia coli | Schistosoma mansoni |
| expressed in Escherichia coli | Fasciola hepatica |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | Schistosoma mansoni | peroxiredoxin induces the expression of Ym1 in macrophages and the development of Th2 immune responses, peroxiredoxin activates macrophages independently of interleukin-4 and interleukin-13 | ? | - |
? |  |
| additional information | Fasciola hepatica | peroxiredoxin induces the expression of Ym1 in macrophages and the development of Th2 immune responses, peroxiredoxin activates macrophages independently of interleukin-4 and interleukin-13 | ? | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Fasciola hepatica | - |
- |
- |
| Schistosoma mansoni | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| nickel-chelate affinity column chromatography | Schistosoma mansoni |
| nickel-chelate affinity column chromatography | Fasciola hepatica |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| additional information | peroxiredoxin induces the expression of Ym1 in macrophages and the development of Th2 immune responses, peroxiredoxin activates macrophages independently of interleukin-4 and interleukin-13 | Schistosoma mansoni | ? | - |
? | |
| additional information | peroxiredoxin induces the expression of Ym1 in macrophages and the development of Th2 immune responses, peroxiredoxin activates macrophages independently of interleukin-4 and interleukin-13 | Fasciola hepatica | ? | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| Prx | - |
Schistosoma mansoni |
| Prx | - |
Fasciola hepatica |
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Release 2023.1 (January 2023)
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