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Literature summary for 1.11.1.12 extracted from

  • Bae, Y.; Cai, G.; Kim, S.; Zo, Y.; Kong, Y.
    Modular evolution of glutathione peroxidase genes in association with different biochemical properties of their encoded proteins in invertebrate animals (2009), BMC Evol. Biol., 9, 72.
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
additional information comparative analysis of invertebrate GPx genes provides information evidence to support the modular pathways of GPx evolution, which have been accompanied with sporadic expansion-deletion and exon-intron remodeling, the study would be beneficial to get detailed insights into the complex GPx evolution, and to understand the molecular basis of the specialized physiological implications of the antioxidant system in their respective organisms animal

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
glutathione + a lipid hydroperoxide animal
-
glutathione disulfide + lipid + H2O
-
?

Organism

Organism UniProt Comment Textmining
animal
-
invertebrate animals, the GPx genes are isolated from various platyhelminths via in silico screening
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
glutathione + a lipid hydroperoxide
-
animal glutathione disulfide + lipid + H2O
-
?

Synonyms

Synonyms Comment Organism
PHGPX
-
animal
phospholipid hydroperoxide glutathione peroxidase
-
animal

Cofactor

Cofactor Comment Organism Structure
glutathione
-
animal