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Literature summary for 1.10.5.1 extracted from

  • Zhou, J.Q.; Zhu, S.Y.; He, Y.; Yu, K.D.
    Association between a tri-allelic polymorphism in the estrogen metabolism oxidoreductase NRH quinone oxidoreductase 2 gene and risk of breast cancer by molecular subtype (2021), Front. Genet., 12, 658285 .
    View publication on PubMedView publication on EuropePMC

Application

Application Comment Organism
medicine an increased risk of breast cancer is associated with the NQ2 I-29 allele. The I-29-containing genotype is significantly correlated with breast cancer under a dominant model. There is a significant association of the I-29/D polymorphism with luminal-like breast cancer but not with HER2-enriched or triple-negative subtypes Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens P16083
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