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Literature summary for 1.10.5.1 extracted from

  • Celli, C.M.; Tran, N.; Knox, R.; Jaiswal, A.K.
    NRH:quinone oxidoreductase 2 (NQO2) catalyzes metabolic activation of quinones and anti-tumor drugs (2006), Biochem. Pharmacol., 72, 366-376.
    View publication on PubMed
Search for more literature for 1.10.5.1

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Chinese hamster ovary cells and Escherichia coli Mus musculus

Inhibitors

Inhibitors Comment Organism Structure
benzo(a)pyrene 20 mM, 90% inhibition Mus musculus
additional information not inhibited by dicoumarol, Cibacron blue, phenindone Mus musculus
quercetin
-
 Mus musculus

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Mus musculus Q9JI75
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
2,6-dichloroindophenol + dihydronicotinamide riboside
-
 Mus musculus ? + nicotinamide riboside
-
 ?
5-(aziridin-1-yl)-2,4-dinitrobenzamide + dihydronicotinamide riboside
-
 Mus musculus ? + nicotinamide riboside
-
 ?
benzo(a)pyrene-3,6-quinone + dihydronicotinamide riboside
-
 Mus musculus ? + nicotinamide riboside
-
 ?
menadione + dihydronicotinamide riboside
-
 Mus musculus menadiol + nicotinamide riboside
-
 ?
mitomycin C + dihydronicotinamide riboside
-
 Mus musculus ? + nicotinamide riboside
-
 ?

Synonyms

Synonyms Comment Organism
NQO2
-
 Mus musculus
NRH:quinone oxidoreductase 2
-
 Mus musculus

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Mus musculus
nicotinamide riboside reduced nicotinamide riboside Mus musculus