Inhibitors | Comment | Organism | Structure |
---|---|---|---|
2-methyl-4-[(E)-(4-nitrophenyl)methylidene]-1,3-oxazol-5(4H)-one | IC50: 0.00351 mM | Agaricus bisporus | |
2-methyl-4-[(E)-2-thienylmethylidene]-1,3-oxazol-5-one | IC50: 0.00311 mM | Agaricus bisporus | |
2-methyl-4-[(E,2Z)-3-phenyl-2-propenyliden]-1,3-oxazol-5(4H)-one | IC50: 0.00123 mM | Agaricus bisporus | |
3-(acetoyloxy)-2-hydroxy-4-[[5-oxo-2-phenyl-1,3-oxazol-4(5H)-ylidene]methyl]phenylacetate | IC50: 0.00215 mM | Agaricus bisporus | |
4-[(E)-(4-nitrophenyl)methylidene]-2-phenyl-1,3-oxazol-5(4H)-one | IC50: 0.00323 mM | Agaricus bisporus | |
kojic acid | IC50: 0.016.67 mM | Agaricus bisporus | |
L-mimosine | IC50: 0.00368 mM | Agaricus bisporus | |
additional information | synthesis and inhibitory potential of seventeen synthesized oxazolone derivatives, structure-activity relationships, overview | Agaricus bisporus |
Metals/Ions | Comment | Organism | Structure |
---|---|---|---|
Cu2+ | copper-containing enzyme | Agaricus bisporus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Agaricus bisporus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
commercial preparation | - |
Agaricus bisporus | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
L-dopa + 1/2 O2 | - |
Agaricus bisporus | L-dopaquinone + H2O | - |
? | |
additional information | multifunctional enzyme | Agaricus bisporus | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
More | cf. 1.14.18.1 | Agaricus bisporus |
tyrosinase | - |
Agaricus bisporus |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.00123 | - |
IC50: 0.00123 mM | Agaricus bisporus | 2-methyl-4-[(E,2Z)-3-phenyl-2-propenyliden]-1,3-oxazol-5(4H)-one | |
0.00215 | - |
IC50: 0.00215 mM | Agaricus bisporus | 3-(acetoyloxy)-2-hydroxy-4-[[5-oxo-2-phenyl-1,3-oxazol-4(5H)-ylidene]methyl]phenylacetate | |
0.00311 | - |
IC50: 0.00311 mM | Agaricus bisporus | 2-methyl-4-[(E)-2-thienylmethylidene]-1,3-oxazol-5-one | |
0.00323 | - |
IC50: 0.00323 mM | Agaricus bisporus | 4-[(E)-(4-nitrophenyl)methylidene]-2-phenyl-1,3-oxazol-5(4H)-one | |
0.00351 | - |
IC50: 0.00351 mM | Agaricus bisporus | 2-methyl-4-[(E)-(4-nitrophenyl)methylidene]-1,3-oxazol-5(4H)-one | |
0.00368 | - |
IC50: 0.00368 mM | Agaricus bisporus | L-mimosine | |
0.016 | - |
IC50: 0.016.67 mM | Agaricus bisporus | kojic acid |