Literature summary for 1.1.99.42 extracted from

Mukherjee, T.; Kinsland, C.; Begley, T.P.
PLP catabolism identification of the 4-pyridoxic acid dehydrogenase gene in Mesorhizobium loti MAFF303099 (2007), Bioorg. Chem., 35, 458-464 .

Search for more literature for 1.1.99.42

Cloned(Commentary)

Cloned (Comment)	Organism
expression in Escherichia coli	Mesorhizobium loti

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.0058	-	4-pyridoxate	pH 8.0, temperature not specified in the publication	Mesorhizobium loti
0.0066	-	NAD+	pH 8.0, temperature not specified in the publication	Mesorhizobium loti

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
4-pyridoxate + NAD+	Mesorhizobium loti	-	5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H+	-	?
4-pyridoxate + NAD+	Mesorhizobium loti MAFF303099	-	5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Mesorhizobium loti	Q988H5	-	-
Mesorhizobium loti MAFF303099	Q988H5	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
4-pyridoxate + NAD+	-	Mesorhizobium loti	5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H+	-	?
4-pyridoxate + NAD+	-	Mesorhizobium loti MAFF303099	5-formyl-3-hydroxy-2-methylpyridine-4-carboxylate + NADH + H+	-	?

Subunits

Subunits	Comment	Organism
?	x * 33000, calculated	Mesorhizobium loti

Synonyms

Synonyms	Comment	Organism
mlr6739	-	Mesorhizobium loti

Turnover Number [1/s]

Turnover Number Minimum [1/s]	Turnover Number Maximum [1/s]	Substrate	Comment	Organism	Structure
0.01	-	NAD+	pH 8.0, temperature not specified in the publication	Mesorhizobium loti

Cofactor

Cofactor	Comment	Organism	Structure
NAD+	-	Mesorhizobium loti

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Release 2023.1 (January 2023)