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Literature summary for 1.1.99.24 extracted from

  • Chen, Q.; Wu, Q.; Peng, Y.
    ADHFE1 is a correlative factor of patient survival in cancer (2021), Open Life Sci., 16, 571-582 .
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.99.24

Application

Application Comment Organism
diagnostics AHDFE1 mRNA expression and DNA methylation can potentially be used as diagnostic markers in cancer and might be of great value in predicting the survival of patients with cancer. High expression of ADHFE1 is positively associated with favorable patient prognosis in breast, colon, and gastric cancers Homo sapiens

Organism

Organism UniProt Comment Textmining
Homo sapiens Q8IWW8
-
-

Source Tissue

Source Tissue Comment Organism Textmining
NCI cell
-
 Homo sapiens
-

Synonyms

Synonyms Comment Organism
ADHFE1
-
 Homo sapiens
alcohol dehydrogenase iron containing 1
-
 Homo sapiens

Expression

Organism Comment Expression
Homo sapiens ADHFE1 expression is regulated by DNA methylation. ADHFE1 is frequently downregulated and hypermethylated in various cancer cell lines and tissue samples. High expression of ADHFE1 is positively associated with favorable patient prognosis in breast, colon, and gastric cancers down

General Information

General Information Comment Organism
malfunction dysregulated ADHFE1 may participate in cancer progression by regulation of metabolic process, DNA replication, and cell cycle Homo sapiens