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Literature summary for 1.1.99.18 extracted from

  • Kracher, D.; Zahma, K.; Schulz, C.; Sygmund, C.; Gorton, L.; Ludwig, R.
    Inter-domain electron transfer in cellobiose dehydrogenase: modulation by pH and divalent cations (2015), FEBS J., 282, 3136-3148.
    View publication on PubMedView publication on EuropePMC
Search for more literature for 1.1.99.18

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.0005
-
 ferricytochrome c in the presence of 30 mM NaCl, at pH 7.5 and 30°C Thermothelomyces myriococcoides
0.0028
-
 ferricytochrome c in the presence of 30 mM NaCl, at pH 5.5 and 30°C Thermothelomyces myriococcoides
0.0043
-
 ferricytochrome c in the presence of 30 mM SrCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
0.0055
-
 ferricytochrome c in the presence of 30 mM BaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
0.0056
-
 ferricytochrome c in the presence of 30 mM CaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
0.0056
-
 ferricytochrome c in the presence of 30 mM MgCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
0.0058
-
 ferricytochrome c in the presence of 30 mM SrCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
0.006
-
 ferricytochrome c in the presence of 30 mM CaCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
0.0061
-
 ferricytochrome c in the presence of 30 mM MgCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
0.0065
-
 ferricytochrome c in the presence of 30 mM BaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides

Metals/Ions

Metals/Ions Comment Organism Structure
Ba2+ activates Thermothelomyces myriococcoides
Cd2+ activates Thermothelomyces myriococcoides
Mg2+ activates Thermothelomyces myriococcoides
Sr2+ activates Thermothelomyces myriococcoides

Organism

Organism UniProt Comment Textmining
Thermothelomyces myriococcoides
-
-
-
Thermothelomyces myriococcoides IIA CBS 208.89
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
cellobiose + 1,4-benzoquinone
-
 Thermothelomyces myriococcoides cellobiono-1,5-lactone + reduced 1,4-benzoquinone
-
 ?
cellobiose + 1,4-benzoquinone
-
 Thermothelomyces myriococcoides IIA CBS 208.89 cellobiono-1,5-lactone + reduced 1,4-benzoquinone
-
 ?
cellobiose + 2,6-dichlorophenolindophenol
-
 Thermothelomyces myriococcoides cellobiono-1,5-lactone + reduced 2,6-dichlorophenolindophenol
-
 ?
cellobiose + 2,6-dichlorophenolindophenol
-
 Thermothelomyces myriococcoides IIA CBS 208.89 cellobiono-1,5-lactone + reduced 2,6-dichlorophenolindophenol
-
 ?
cellobiose + ferricyanide
-
 Thermothelomyces myriococcoides cellobiono-1,5-lactone + ferrocyanide
-
 ?
cellobiose + ferricyanide
-
 Thermothelomyces myriococcoides IIA CBS 208.89 cellobiono-1,5-lactone + ferrocyanide
-
 ?
cellobiose + ferricytochrome c
-
 Thermothelomyces myriococcoides cellobiono-1,5-lactone + ferrocytochrome c
-
 ?
cellobiose + ferricytochrome c
-
 Thermothelomyces myriococcoides IIA CBS 208.89 cellobiono-1,5-lactone + ferrocytochrome c
-
 ?
cellobiose + ferrocenium
-
 Thermothelomyces myriococcoides cellobiono-1,5-lactone + reduced ferrocenium
-
 ?
cellobiose + ferrocenium
-
 Thermothelomyces myriococcoides IIA CBS 208.89 cellobiono-1,5-lactone + reduced ferrocenium
-
 ?

Synonyms

Synonyms Comment Organism
Cdh
-
 Thermothelomyces myriococcoides

Turnover Number [1/s]

Turnover Number Minimum [1/s] Turnover Number Maximum [1/s] Substrate Comment Organism Structure
0.01
-
 ferricytochrome c in the presence of 30 mM NaCl, at pH 7.5 and 30°C Thermothelomyces myriococcoides
0.4
-
 ferricytochrome c in the presence of 30 mM NaCl, at pH 5.5 and 30°C Thermothelomyces myriococcoides
1.4
-
 ferricytochrome c in the presence of 30 mM CaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
1.4
-
 ferricytochrome c in the presence of 30 mM SrCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
1.5
-
 ferricytochrome c in the presence of 30 mM BaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
1.6
-
 ferricytochrome c in the presence of 30 mM CaCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
1.6
-
 ferricytochrome c in the presence of 30 mM MgCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
2
-
 ferricytochrome c in the presence of 30 mM BaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
2
-
 ferricytochrome c in the presence of 30 mM SrCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
2.1
-
 ferricytochrome c in the presence of 30 mM MgCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
5
-
 with ferricytochrome c as cosubtrate Thermothelomyces myriococcoides
5.5
-
 with 2,6-dichlorophenolindophenol as cosubtrate Thermothelomyces myriococcoides

Cofactor

Cofactor Comment Organism Structure
FAD
-
 Thermothelomyces myriococcoides
heme b
-
 Thermothelomyces myriococcoides

pI Value

Organism Comment pI Value Maximum pI Value
Thermothelomyces myriococcoides isoelectric focusing
-
 3.8

kcat/KM [mM/s]

kcat/KM Value [1/mMs-1] kcat/KM Value Maximum [1/mMs-1] Substrate Comment Organism Structure
20
-
 ferricytochrome c in the presence of 30 mM NaCl, at pH 7.5 and 30°C Thermothelomyces myriococcoides
143
-
 ferricytochrome c in the presence of 30 mM NaCl, at pH 5.5 and 30°C Thermothelomyces myriococcoides
250
-
 ferricytochrome c in the presence of 30 mM CaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
267
-
 ferricytochrome c in the presence of 30 mM CaCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
273
-
 ferricytochrome c in the presence of 30 mM BaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
286
-
 ferricytochrome c in the presence of 30 mM MgCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
308
-
 ferricytochrome c in the presence of 30 mM BaCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
326
-
 ferricytochrome c in the presence of 30 mM SrCl2, at pH 5.5 and 30°C Thermothelomyces myriococcoides
344
-
 ferricytochrome c in the presence of 30 mM MgCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides
345
-
 ferricytochrome c in the presence of 30 mM SrCl2, at pH 7.5 and 30°C Thermothelomyces myriococcoides