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Literature summary for 1.1.98.7 extracted from

  • Benjdia, A.; Subramanian, S.; Leprince, J.; Vaudry, H.; Johnson, M.K.; Berteau, O.
    Anaerobic sulfatase-maturating enzymes, first dual substrate radical S-adenosylmethionine enzymes (2008), J. Biol. Chem., 283, 17815-26.
    View publication on PubMedView publication on EuropePMC

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli BL21(DE3) Bacteroides thetaiotaomicron

Metals/Ions

Metals/Ions Comment Organism Structure
[4Fe-4S] cluster
-
Bacteroides thetaiotaomicron

Organism

Organism UniProt Comment Textmining
Bacteroides thetaiotaomicron Q02550
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Bacteroides thetaiotaomicron DSM 2079 Q02550
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-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
Ac-FENAYTAVPSSIASRASILTGMS-NH2 + S-adenosyl-L-methionine
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Bacteroides thetaiotaomicron Ac-FENAYTAVPS-3-oxo-L-Ala-IASRASILTGMS-NH2 + L-methionine + 5'-deoxyadenosine
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?
Ac-FENAYTAVPSSIASRASILTGMS-NH2 + S-adenosyl-L-methionine
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Bacteroides thetaiotaomicron DSM 2079 Ac-FENAYTAVPS-3-oxo-L-Ala-IASRASILTGMS-NH2 + L-methionine + 5'-deoxyadenosine
-
?
additional information the enzyme converts a serine residue of arylsulfatase into a 3-oxo-L-alanine residue. The post-translational modification of sulfatases, i.e. the creation of a 3-oxo-L-alanine (i.e. Calpha-formylglycine) residue from a cysteine or serine is vital for the proper function of sulfatases Bacteroides thetaiotaomicron ?
-
?
additional information the enzyme converts a serine residue of arylsulfatase into a 3-oxo-L-alanine residue. The post-translational modification of sulfatases, i.e. the creation of a 3-oxo-L-alanine (i.e. Calpha-formylglycine) residue from a cysteine or serine is vital for the proper function of sulfatases Bacteroides thetaiotaomicron DSM 2079 ?
-
?

Synonyms

Synonyms Comment Organism
anaerobic sulfatase-maturating enzyme
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Bacteroides thetaiotaomicron
anSME
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Bacteroides thetaiotaomicron

General Information

General Information Comment Organism
metabolism involved in the maturation of sulfatases Bacteroides thetaiotaomicron