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Literature summary for 1.1.5.11 extracted from
- Roles for the two 1-butanol dehydrogenases of Pseudomonas butanovora in butane and 1-butanol metabolism (2002), J. Bacteriol., 184, 4343-4350.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| antimycin A | 3% inhibition at 1 mM | Thauera butanivorans |  |
| additional information | not inhibited by cyanide (1 mM) | Thauera butanivorans | |
| Salicylhydroxamic acid | 5% inhibition at 3 mM | Thauera butanivorans | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.0017 | - |
butan-1-ol | at pH 7.0 and 30°C | Thauera butanivorans | |
| 0.369 | - |
Butyraldehyde | at pH 7.0 and 30°C | Thauera butanivorans | |
| 0.662 | - |
2-butanol | at pH 7.0 and 30°C | Thauera butanivorans | |
Localization
| Localization | Comment | Organism | GeneOntology No. | Textmining |
|---|---|---|---|---|
| periplasm | - |
Thauera butanivorans | - |
- |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| butan-1-ol + a quinone | Thauera butanivorans | - |
butanal + a quinol | - |
? | |
| butan-1-ol + a quinone | Thauera butanivorans ATCC 43655 | - |
butanal + a quinol | - |
? | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Thauera butanivorans | - |
- |
- |
| Thauera butanivorans ATCC 43655 | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
| Q-Sepharose column chromatography and Superose 6 gel filtration | Thauera butanivorans |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| 2-butanol + a quinone | - |
Thauera butanivorans | 2-butanone + a quinol | - |
? | |
| 2-butanol + a quinone | - |
Thauera butanivorans ATCC 43655 | 2-butanone + a quinol | - |
? | |
| butan-1-ol + a quinone | - |
Thauera butanivorans | butanal + a quinol | - |
? | |
| butan-1-ol + a quinone | - |
Thauera butanivorans ATCC 43655 | butanal + a quinol | - |
? | |
| butyraldehyde + a quinol | - |
Thauera butanivorans | 1-butanol + a quinone | - |
? | |
| butyraldehyde + a quinol | - |
Thauera butanivorans ATCC 43655 | 1-butanol + a quinone | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 1-butanol dehydrogenase | - |
Thauera butanivorans |
| BOH | - |
Thauera butanivorans |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| pyrroloquinoline quinone | - |
Thauera butanivorans | |
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