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Literature summary for 1.1.3.8 extracted from

  • Birney, E.C.; Jenness, R.; Hume, I.D.
    Ascorbic acid biosynthesis in the mammalian kidney (1979), Experientia, 35, 1425-1426.
    View publication on PubMed
Search for more literature for 1.1.3.8

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
L-gulono-1,4-lactone + O2 Tachyglossus aculeatus
-
 L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2 Ornithorhynchus anatinus
-
 L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2 Perameles nasuta
-
 L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2 Isoodon macrourus
-
 L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2 Notamacropus rufogriseus
-
 L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2 Thylogale thetis
-
 L-xylo-hex-3-ulonolactone + H2O2
-
 ?

Organism

Organism UniProt Comment Textmining
Isoodon macrourus
-
 brindled bandicoot
-
Notamacropus rufogriseus
-
-
-
Ornithorhynchus anatinus
-
-
-
Perameles nasuta
-
 long-nosed bandicoot
-
Tachyglossus aculeatus
-
-
-
Thylogale thetis
-
-
-

Reaction

Reaction Comment Organism Reaction ID
L-gulono-1,4-lactone + O2 = L-xylo-hex-2-ulono-1,4-lactone + H2O2 product isomerizes spontaneously to L-ascorbate Tachyglossus aculeatus
a
L-gulono-1,4-lactone + O2 = L-xylo-hex-2-ulono-1,4-lactone + H2O2 product isomerizes spontaneously to L-ascorbate Ornithorhynchus anatinus
a
L-gulono-1,4-lactone + O2 = L-xylo-hex-2-ulono-1,4-lactone + H2O2 product isomerizes spontaneously to L-ascorbate Perameles nasuta
a
L-gulono-1,4-lactone + O2 = L-xylo-hex-2-ulono-1,4-lactone + H2O2 product isomerizes spontaneously to L-ascorbate Isoodon macrourus
a
L-gulono-1,4-lactone + O2 = L-xylo-hex-2-ulono-1,4-lactone + H2O2 product isomerizes spontaneously to L-ascorbate Notamacropus rufogriseus
a
L-gulono-1,4-lactone + O2 = L-xylo-hex-2-ulono-1,4-lactone + H2O2 product isomerizes spontaneously to L-ascorbate Thylogale thetis
a

Source Tissue

Source Tissue Comment Organism Textmining
kidney relatively high levels of gulonolactone oxidase in kidney and liver Perameles nasuta
-
kidney relatively high levels of gulonolactone oxidase in kidney and liver Isoodon macrourus
-
kidney primary locus of ascorbate is in liver Tachyglossus aculeatus
-
kidney primary locus of ascorbate is in liver Ornithorhynchus anatinus
-
liver relatively high levels of gulonolactone oxidase in kidney and liver Perameles nasuta
-
liver relatively high levels of gulonolactone oxidase in kidney and liver Isoodon macrourus
-
liver primary locus of ascorbate is in liver Notamacropus rufogriseus
-
liver primary locus of ascorbate is in liver Thylogale thetis
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
L-gulono-1,4-lactone + O2
-
 Tachyglossus aculeatus L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2
-
 Ornithorhynchus anatinus L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2
-
 Perameles nasuta L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2
-
 Isoodon macrourus L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2
-
 Notamacropus rufogriseus L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2
-
 Thylogale thetis L-xylo-hex-3-ulonolactone + H2O2
-
 ?
L-gulono-1,4-lactone + O2
-
 Tachyglossus aculeatus L-xylo-hex-3-ulonolactone + H2O2 product isomerizes spontaneously to L-ascorbate ?
L-gulono-1,4-lactone + O2
-
 Ornithorhynchus anatinus L-xylo-hex-3-ulonolactone + H2O2 product isomerizes spontaneously to L-ascorbate ?
L-gulono-1,4-lactone + O2
-
 Perameles nasuta L-xylo-hex-3-ulonolactone + H2O2 product isomerizes spontaneously to L-ascorbate ?
L-gulono-1,4-lactone + O2
-
 Isoodon macrourus L-xylo-hex-3-ulonolactone + H2O2 product isomerizes spontaneously to L-ascorbate ?
L-gulono-1,4-lactone + O2
-
 Notamacropus rufogriseus L-xylo-hex-3-ulonolactone + H2O2 product isomerizes spontaneously to L-ascorbate ?
L-gulono-1,4-lactone + O2
-
 Thylogale thetis L-xylo-hex-3-ulonolactone + H2O2 product isomerizes spontaneously to L-ascorbate ?