Literature summary for 1.1.3.47 extracted from

Yuan, H.; Li, J.; Shin, H.D.; Du, G.; Chen, J.; Shi, Z.; Liu, L.
Improved production of 2,5-furandicarboxylic acid by overexpression of 5-hydroxymethylfurfural oxidase and 5-hydroxymethylfurfural/furfural oxidoreductase in Raoultella ornithinolytica BF60 (2018), Biores. Technol., 247, 1184-1188 .

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Application

Application	Comment	Organism
synthesis	production of 2,5-furandicarboxylic acid by biotransformation of 5-hydroxymethylfurfural. Genes encoding 5-hydroxymethylfurfural oxidase and 5-hydroxymethylfurfural/furfural oxidoreductase from Cupriavidus basilensis HMF14 are introduced into Raoultella ornithinolytica BF60. The 2,5-furandicarboxylic acid production in the engineered whole-cell biocatalyst increases from 51.0 to 93.6 mM, and the molar conversion ratio of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid increases from 51.0 to 93.6%	Methylovorus sp. MP688

Protein Variants

Protein Variants	Comment	Organism
synthesis	expression of HMFO and HMF/furfural oxidoreductase HmfH from Cupriavidus basilensis HMF14 in Raoultella ornithinolytica BF60 results in an increase in 2,5-furandicarboxylic acid production from 51.0 to 93.6 mM, and the molar conversion ratio of 5-hydroxymethylfurfural to 2,5-furandicarboxylic acid increases from 51.0 to 93.6%	Methylovorus sp. MP688

Organism

Organism	UniProt	Comment	Textmining
Methylovorus sp. MP688	E4QP00	-	-

Synonyms

Synonyms	Comment	Organism
HMFO	-	Methylovorus sp. MP688

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Release 2023.1 (January 2023)