BRENDA - Enzyme Database show
show all sequences of 1.1.3.40

Centrifugal evidence for association of mannitol oxidase with distinct organelles ('mannosomes') in the digestive gland of several species of terrestrial gastropod mollusc

Large, A.T.; Connock, M.J.; Comp. Biochem. Physiol. A 107, 621-629 (1994)
No PubMed abstract available

Data extracted from this reference:

KM Value [mM]
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
9.3
-
D-mannitol
digestive gland
Helix aspersa
13.7
-
D-mannitol
digestive gland
Helix aspersa
13.7
-
D-mannitol
-
Limax flavus
15.4
-
D-mannitol
-
Arion ater
15.4
-
D-mannitol
digestive gland
Helix aspersa
17.3
-
D-arabinitol
digestive gland
Helix aspersa
21.5
-
D-arabinitol
digestive gland
Helix aspersa
21.5
-
D-arabinitol
-
Limax flavus
54.6
-
D-arabinitol
-
Arion ater
54.6
-
D-arabinitol
digestive gland
Helix aspersa
Localization
Localization
Commentary
Organism
GeneOntology No.
Textmining
mannosome
the enzyme from the snails Helix aspersa, Arion ater and Arion lucitanicus is found in a specialised tubular distinct organelle that has been termed the mannosome, they commonly have a hexagonal arrangement surrounded by smooth membrane and enclose a central tubule
Arion ater
42580
-
mannosome
the enzyme from the snails Helix aspersa, Arion ater and Arion lucitanicus is found in a specialised tubular distinct organelle that has been termed the mannosome, they commonly have a hexagonal arrangement surrounded by smooth membrane and enclose a central tubule
Arion lusitanicus
42580
-
mannosome
the enzyme from the snails Helix aspersa, Arion ater and Arion lucitanicus is found in a specialised tubular distinct organelle that has been termed the mannosome, they commonly have a hexagonal arrangement surrounded by smooth membrane and enclose a central tubule
Helix aspersa
42580
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Arion ater
-
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Arion lusitanicus
-
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Helix aspersa
-
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Limax flavus
-
-
Natural Substrates/ Products (Substrates)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-mannitol + O2
Helix aspersa
-
mannose + H2O2
-
-
?
D-mannitol + O2
Arion ater
-
mannose + H2O2
-
-
?
D-mannitol + O2
Arion lusitanicus
-
mannose + H2O2
-
-
?
D-mannitol + O2
Limax flavus
-
mannose + H2O2
-
-
?
Organism
Organism
Primary Accession No. (UniProt)
Commentary
Textmining
Arion ater
-
Arion empiricorum; terrestrial slug
-
Arion lusitanicus
-
terrestrial gastropod mollusc, slug
-
Helix aspersa
-
common garden snail; terrestrial snail
-
Limax flavus
-
terrestrial gastropod mollusc, slug
-
Source Tissue
Source Tissue
Commentary
Organism
Textmining
alimentary canal
-
Helix aspersa
-
digestive gland
-
Arion ater
-
digestive gland
-
Arion lusitanicus
-
digestive gland
-
Helix aspersa
-
digestive gland
-
Limax flavus
-
gut
-
Arion ater
-
gut
-
Helix aspersa
-
Substrates and Products (Substrate)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-arabinitol + O2
best substrate
287633
Helix aspersa
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
best substrate
287633
Arion ater
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
best substrate
287633
Limax flavus
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
arabitol
287633
Helix aspersa
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
arabitol
287633
Arion ater
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
arabitol
287633
Limax flavus
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
122% activity compared with D-mannitol
287633
Helix aspersa
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
118% activity compared with D-mannitol
287633
Arion ater
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
136% activity compared with D-mannitol
287633
Limax flavus
arabinose + H2O2
-
-
-
?
D-glucitol + O2
sorbitol
287633
Helix aspersa
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
sorbitol
287633
Arion ater
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
sorbitol
287633
Limax flavus
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
19.4% activity compared with D-mannitol
287633
Arion ater
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
26.5% activity compared with D-mannitol
287633
Helix aspersa
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
19.1% activity compared with D-mannitol
287633
Limax flavus
D-glucose + H2O2
-
-
-
-
D-mannitol + O2
-
287633
Helix aspersa
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287633
Arion ater
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287633
Arion lusitanicus
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287633
Limax flavus
mannose + H2O2
-
-
-
?
additional information
substrate specificity
287633
Helix aspersa
?
-
-
-
-
additional information
substrate specificity
287633
Arion ater
?
-
-
-
-
additional information
substrate specificity
287633
Limax flavus
?
-
-
-
-
additional information
ribitol and xylitol: no substrates
287633
Helix aspersa
?
-
-
-
-
additional information
ribitol and xylitol: no substrates
287633
Arion ater
?
-
-
-
-
additional information
ribitol and xylitol: no substrates
287633
Limax flavus
?
-
-
-
-
Temperature Optimum [°C]
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
23
-
assay at
Arion ater
23
-
assay at
Arion lusitanicus
23
-
assay at
Helix aspersa
23
-
assay at
Limax flavus
KM Value [mM] (protein specific)
KM Value [mM]
KM Value Maximum [mM]
Substrate
Commentary
Organism
Structure
9.3
-
D-mannitol
digestive gland
Helix aspersa
13.7
-
D-mannitol
digestive gland
Helix aspersa
13.7
-
D-mannitol
-
Limax flavus
15.4
-
D-mannitol
-
Arion ater
15.4
-
D-mannitol
digestive gland
Helix aspersa
17.3
-
D-arabinitol
digestive gland
Helix aspersa
21.5
-
D-arabinitol
digestive gland
Helix aspersa
21.5
-
D-arabinitol
-
Limax flavus
54.6
-
D-arabinitol
-
Arion ater
54.6
-
D-arabinitol
digestive gland
Helix aspersa
Localization (protein specific)
Localization
Commentary
Organism
GeneOntology No.
Textmining
mannosome
the enzyme from the snails Helix aspersa, Arion ater and Arion lucitanicus is found in a specialised tubular distinct organelle that has been termed the mannosome, they commonly have a hexagonal arrangement surrounded by smooth membrane and enclose a central tubule
Arion ater
42580
-
mannosome
the enzyme from the snails Helix aspersa, Arion ater and Arion lucitanicus is found in a specialised tubular distinct organelle that has been termed the mannosome, they commonly have a hexagonal arrangement surrounded by smooth membrane and enclose a central tubule
Arion lusitanicus
42580
-
mannosome
the enzyme from the snails Helix aspersa, Arion ater and Arion lucitanicus is found in a specialised tubular distinct organelle that has been termed the mannosome, they commonly have a hexagonal arrangement surrounded by smooth membrane and enclose a central tubule
Helix aspersa
42580
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Arion ater
-
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Arion lusitanicus
-
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Helix aspersa
-
-
additional information
analytical subcellular fractionation experiments; histochemical and biochemical localization; subcellular localization
Limax flavus
-
-
Natural Substrates/ Products (Substrates) (protein specific)
Natural Substrates
Organism
Commentary (Nat. Sub.)
Natural Products
Commentary (Nat. Pro.)
Organism (Nat. Pro.)
Reversibility
D-mannitol + O2
Helix aspersa
-
mannose + H2O2
-
-
?
D-mannitol + O2
Arion ater
-
mannose + H2O2
-
-
?
D-mannitol + O2
Arion lusitanicus
-
mannose + H2O2
-
-
?
D-mannitol + O2
Limax flavus
-
mannose + H2O2
-
-
?
Source Tissue (protein specific)
Source Tissue
Commentary
Organism
Textmining
alimentary canal
-
Helix aspersa
-
digestive gland
-
Arion ater
-
digestive gland
-
Arion lusitanicus
-
digestive gland
-
Helix aspersa
-
digestive gland
-
Limax flavus
-
gut
-
Arion ater
-
gut
-
Helix aspersa
-
Substrates and Products (Substrate) (protein specific)
Substrates
Commentary Substrates
Literature (Substrates)
Organism
Products
Commentary (Products)
Literature (Products)
Organism (Products)
Reversibility
D-arabinitol + O2
best substrate
287633
Helix aspersa
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
best substrate
287633
Arion ater
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
best substrate
287633
Limax flavus
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
arabitol
287633
Helix aspersa
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
arabitol
287633
Arion ater
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
arabitol
287633
Limax flavus
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
122% activity compared with D-mannitol
287633
Helix aspersa
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
118% activity compared with D-mannitol
287633
Arion ater
arabinose + H2O2
-
-
-
?
D-arabinitol + O2
136% activity compared with D-mannitol
287633
Limax flavus
arabinose + H2O2
-
-
-
?
D-glucitol + O2
sorbitol
287633
Helix aspersa
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
sorbitol
287633
Arion ater
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
sorbitol
287633
Limax flavus
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
19.4% activity compared with D-mannitol
287633
Arion ater
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
26.5% activity compared with D-mannitol
287633
Helix aspersa
D-glucose + H2O2
-
-
-
-
D-glucitol + O2
19.1% activity compared with D-mannitol
287633
Limax flavus
D-glucose + H2O2
-
-
-
-
D-mannitol + O2
-
287633
Helix aspersa
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287633
Arion ater
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287633
Arion lusitanicus
mannose + H2O2
-
-
-
?
D-mannitol + O2
-
287633
Limax flavus
mannose + H2O2
-
-
-
?
additional information
substrate specificity
287633
Helix aspersa
?
-
-
-
-
additional information
substrate specificity
287633
Arion ater
?
-
-
-
-
additional information
substrate specificity
287633
Limax flavus
?
-
-
-
-
additional information
ribitol and xylitol: no substrates
287633
Helix aspersa
?
-
-
-
-
additional information
ribitol and xylitol: no substrates
287633
Arion ater
?
-
-
-
-
additional information
ribitol and xylitol: no substrates
287633
Limax flavus
?
-
-
-
-
Temperature Optimum [°C] (protein specific)
Temperature Optimum [°C]
Temperature Optimum Maximum [°C]
Commentary
Organism
23
-
assay at
Arion ater
23
-
assay at
Arion lusitanicus
23
-
assay at
Helix aspersa
23
-
assay at
Limax flavus
Other publictions for EC 1.1.3.40
No.
1st author
Pub Med
title
organims
journal
volume
pages
year
Activating Compound
Application
Cloned(Commentary)
Crystallization (Commentary)
Engineering
General Stability
Inhibitors
KM Value [mM]
Localization
Metals/Ions
Molecular Weight [Da]
Natural Substrates/ Products (Substrates)
Organic Solvent Stability
Organism
Oxidation Stability
Posttranslational Modification
Purification (Commentary)
Reaction
Renatured (Commentary)
Source Tissue
Specific Activity [micromol/min/mg]
Storage Stability
Substrates and Products (Substrate)
Subunits
Temperature Optimum [°C]
Temperature Range [°C]
Temperature Stability [°C]
Turnover Number [1/s]
pH Optimum
pH Range
pH Stability
Cofactor
Ki Value [mM]
pI Value
IC50 Value
Activating Compound (protein specific)
Application (protein specific)
Cloned(Commentary) (protein specific)
Cofactor (protein specific)
Crystallization (Commentary) (protein specific)
Engineering (protein specific)
General Stability (protein specific)
IC50 Value (protein specific)
Inhibitors (protein specific)
Ki Value [mM] (protein specific)
KM Value [mM] (protein specific)
Localization (protein specific)
Metals/Ions (protein specific)
Molecular Weight [Da] (protein specific)
Natural Substrates/ Products (Substrates) (protein specific)
Organic Solvent Stability (protein specific)
Oxidation Stability (protein specific)
Posttranslational Modification (protein specific)
Purification (Commentary) (protein specific)
Renatured (Commentary) (protein specific)
Source Tissue (protein specific)
Specific Activity [micromol/min/mg] (protein specific)
Storage Stability (protein specific)
Substrates and Products (Substrate) (protein specific)
Subunits (protein specific)
Temperature Optimum [°C] (protein specific)
Temperature Range [°C] (protein specific)
Temperature Stability [°C] (protein specific)
Turnover Number [1/s] (protein specific)
pH Optimum (protein specific)
pH Range (protein specific)
pH Stability (protein specific)
pI Value (protein specific)
Expression
General Information
General Information (protein specific)
Expression (protein specific)
KCat/KM [mM/s]
KCat/KM [mM/s] (protein specific)
655277
Knigge
Mannosomes: a molluscan intrac ...
Arion lusitanicus
Comp. Biochem. Physiol. C
131
259-269
2002
-
-
-
-
-
-
3
-
1
-
-
-
-
4
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
3
-
-
1
-
-
-
-
-
-
-
-
1
-
-
1
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287633
Large
-
Centrifugal evidence for assoc ...
Arion ater, Arion lusitanicus, Helix aspersa, Limax flavus
Comp. Biochem. Physiol. A
107
621-629
1994
-
-
-
-
-
-
-
10
7
-
-
4
-
4
-
-
-
-
-
7
-
-
25
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
10
7
-
-
4
-
-
-
-
-
7
-
-
25
-
4
-
-
-
-
-
-
-
-
-
-
-
-
-
287630
Large
-
The association of mannitol ox ...
Arion ater
Protoplasma
175
93-101
1993
-
-
-
-
-
-
-
-
2
-
-
2
-
1
-
-
-
-
-
1
-
-
3
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
-
2
-
-
2
-
-
-
-
-
1
-
-
3
2
-
-
-
-
-
-
-
-
-
-
-
-
-
-
287632
Malik
-
Assay and subcellular localiza ...
Arion ater
J. Exp. Zool.
242
9-15
1987
-
-
-
-
-
-
-
1
4
-
-
2
-
1
-
-
-
-
-
4
1
-
3
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
1
4
-
-
2
-
-
-
-
-
4
1
-
3
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-
287629
Vorhaben
Mannitol oxidase: partial puri ...
Helix aspersa
Int. J. Biochem.
18
337-344
1986
1
-
-
-
-
2
3
2
2
-
1
2
-
2
-
1
1
1
-
5
1
3
16
2
1
-
-
-
2
1
2
1
-
-
-
1
-
-
1
-
-
2
-
3
-
2
2
-
1
2
-
-
1
1
-
5
1
3
16
2
1
-
-
-
2
1
2
-
-
-
-
-
-
-
287631
Vorhaben
-
Histochemical and biochemical ...
Biomphalaria glabrata, Helix aspersa
J. Exp. Zool.
231
157-160
1984
-
-
-
-
-
-
-
-
4
-
-
3
-
2
-
-
1
-
-
15
1
-
8
-
1
-
-
-
1
-
-
1
-
-
-
-
-
-
1
-
-
-
-
-
-
-
4
-
-
3
-
-
-
1
-
15
1
-
8
-
1
-
-
-
1
-
-
-
-
-
-
-
-
-