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Literature summary for 1.1.1.B4 extracted from

  • Peng, Y.; Zhang, Y.
    Continuous preparation of (R)-phenyl-ethanediol by catalysis of nanoparticles immobilized bi-enzyme coupling system (2016), Chin. J. Proc. Engin., 16, 286-291 .
No PubMed abstract available

Application

Application Comment Organism
synthesis the enzyme is coupled with formate dehydrogenase and co-immobilized on SiO2 particles, the system is used for continuous catalytic conversion of beta-hydroxyacetophenone to optically pure (r)-phenylethanediol with in situ NADH regeneration and recycling. Reusable system, method overview Morganella morganii

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
(R)-1-phenylethanol + NAD+ Morganella morganii
-
acetophenone + NADH + H+
-
?
(R)-1-phenylethanol + NAD+ Morganella morganii CMCC(B)49208
-
acetophenone + NADH + H+
-
?

Organism

Organism UniProt Comment Textmining
Morganella morganii
-
-
-
Morganella morganii CMCC(B)49208
-
-
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(R)-1-phenylethanol + NAD+
-
Morganella morganii acetophenone + NADH + H+
-
?
(R)-1-phenylethanol + NAD+
-
Morganella morganii CMCC(B)49208 acetophenone + NADH + H+
-
?
additional information the enzyme is coupled with formate dehydrogenase and co-immobilized on SiO2 particles, the system is capable for continuous catalytic conversion of beta-hydroxyacetophenone to optically pure (R)-phenylethanediol with in situ NADH regeneration and recycling, reusable system, method overview Morganella morganii ?
-
?
additional information the enzyme is coupled with formate dehydrogenase and co-immobilized on SiO2 particles, the system is capable for continuous catalytic conversion of beta-hydroxyacetophenone to optically pure (R)-phenylethanediol with in situ NADH regeneration and recycling, reusable system, method overview Morganella morganii CMCC(B)49208 ?
-
?

Synonyms

Synonyms Comment Organism
carbonyl reductase
-
Morganella morganii
mLDH
-
Morganella morganii

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
40
-
in the coupled nanaparticle-immobilized system Morganella morganii

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
6.5
-
in the coupled nanaparticle-immobilized system Morganella morganii

Cofactor

Cofactor Comment Organism Structure
NAD+
-
Morganella morganii