Inhibitors | Comment | Organism | Structure |
---|---|---|---|
additional information | peptic and tryptic soybean hydrolysates (2.5 mg/ml) inhibit the 3-hydroxy-3-methylglutaryl-CoA reductase activity in Hep-G2 cells by 16% and 76.9%, respectively | Homo sapiens |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-mevalonate + CoA + 2 NAD+ | Homo sapiens | - |
(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
Hep-G2 cell | - |
Homo sapiens | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(R)-mevalonate + CoA + 2 NAD+ | - |
Homo sapiens | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
3-hydroxy-3-methylglutaryl coenzyme A reductase | - |
Homo sapiens |
3-hydroxy-3-methylglutaryl-CoA reductase | - |
Homo sapiens |
HMGCoAR | - |
Homo sapiens |