Any feedback?
Literature summary for 1.1.1.88 extracted from
- Soybean peptides exert multifunctional bioactivity modulating 3-hydroxy-3-methylglutaryl-CoA reductase and dipeptidyl peptidase-IV targets in vitro (2019), J. Agric. Food Chem., 67, 4824-4830 .
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| additional information | peptic and tryptic soybean hydrolysates (2.5 mg/ml) inhibit the 3-hydroxy-3-methylglutaryl-CoA reductase activity in Hep-G2 cells by 16% and 76.9%, respectively | Homo sapiens |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (R)-mevalonate + CoA + 2 NAD+ | Homo sapiens | - |
(S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ | - |
? |  |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | - |
- |
- |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| Hep-G2 cell | - |
Homo sapiens | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (R)-mevalonate + CoA + 2 NAD+ | - |
Homo sapiens | (S)-3-hydroxy-3-methylglutaryl-CoA + 2 NADH + 2 H+ | - |
? | |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 3-hydroxy-3-methylglutaryl coenzyme A reductase | - |
Homo sapiens |
| 3-hydroxy-3-methylglutaryl-CoA reductase | - |
Homo sapiens |
| HMGCoAR | - |
Homo sapiens |
Use of this online version of BRENDA is free under the CC BY 4.0 license. See terms of use for full details.
Release 2023.1 (January 2023)
Legal
Curated at
Member of
