Activating Compound | Comment | Organism | Structure |
---|---|---|---|
docosahexaenoic acid ethyl ester | in 18-month-old aged mice but not in 8-month-old mice, HMG-CoA reductase activity is enhanced with dietary intake of docosahexaenoic acid ethyl ester (DHA-EE) | Mus musculus |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mus musculus | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
brain | results show that docosahexaenoic acid ethyl ester enhances brain HMG-CoA reductase activity in aged mice | Mus musculus | - |
liver | - |
Mus musculus | - |
Specific Activity Minimum [µmol/min/mg] | Specific Activity Maximum [µmol/min/mg] | Comment | Organism |
---|---|---|---|
additional information | - |
after a dietary intake of docosahexaenoic acid ethyl ester (DHA-EE) brain HMG-CoA reductase activity and brain cholesterol content significantly increases with age. Hepatic HMG-CoA reductase activity and the cholesterol content of both adult and aged mice are reduced in DHA-EE diet groups compared with linoleic acid ethyl ester | Mus musculus |
Synonyms | Comment | Organism |
---|---|---|
HMG-CoA reductase | - |
Mus musculus |
Temperature Optimum [°C] | Temperature Optimum Maximum [°C] | Comment | Organism |
---|---|---|---|
37 | - |
assay at | Mus musculus |
pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
---|---|---|---|
7.2 | - |
assay at | Mus musculus |