Cloned (Comment) | Organism |
---|---|
expression in Catharanthus roseus, the hairy roots with higher levels of soluble enzyme, clone 19, have a lower alkaloid and higher sterol content. By contrast, the clone with nonsoluble enzyme activity, clone 236, has a higher alkaloid and lower sterol content | Mesocricetus auratus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-3-methyl-glutaryl-CoA + NADH + H+ | Mesocricetus auratus | mevalonate pathway | mevalonate + CoA + NAD+ | - |
? | |
additional information | Mesocricetus auratus | The enzyme can play a role in indole alkaloid biosynthesis and a possible cosuppression of both the endogenous and foreign enzyme genes in clone 236 | ? | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Mesocricetus auratus | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3-hydroxy-3-methyl-glutaryl-CoA + NADH + H+ | - |
Mesocricetus auratus | mevalonate + CoA + NAD+ | - |
? | |
3-hydroxy-3-methyl-glutaryl-CoA + NADH + H+ | mevalonate pathway | Mesocricetus auratus | mevalonate + CoA + NAD+ | - |
? | |
additional information | The enzyme can play a role in indole alkaloid biosynthesis and a possible cosuppression of both the endogenous and foreign enzyme genes in clone 236 | Mesocricetus auratus | ? | - |
? |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Mesocricetus auratus | |
NADH | - |
Mesocricetus auratus |