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Literature summary for 1.1.1.78 extracted from

  • Ting, S.M.; Miller, O.N.; Sellinger, O.Z.
    The metabolism of lactaldehyde: VII. The oxidation of D-lactaldehyde in rat liver (1965), Biochim. Biophys. Acta, 97, 407-415.
    View publication on PubMed
Search for more literature for 1.1.1.78

Inhibitors

Inhibitors Comment Organism Structure
iodoacetate
-
 Rattus norvegicus
N-ethylmaleimide
-
 Rattus norvegicus
p-chloromercuribenzoate
-
 Rattus norvegicus

KM Value [mM]

KM Value [mM] KM Value Maximum [mM] Substrate Comment Organism Structure
0.013
-
 DL-lactaldehyde
-
 Rattus norvegicus
0.034
-
 NAD+
-
 Rattus norvegicus

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
methylglyoxal + NADH Rattus norvegicus
-
 (R)-lactaldehyde + NAD+
-
 r

Organism

Organism UniProt Comment Textmining
Rattus norvegicus
-
-
-

Purification (Commentary)

Purification (Comment) Organism
-
 Rattus norvegicus

Source Tissue

Source Tissue Comment Organism Textmining
brain
-
 Rattus norvegicus
-
heart
-
 Rattus norvegicus
-
kidney
-
 Rattus norvegicus
-
liver
-
 Rattus norvegicus
-
lung
-
 Rattus norvegicus
-
skeletal muscle highest activity Rattus norvegicus
-
spleen
-
 Rattus norvegicus
-

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
DL-glyceraldehyde + NAD+
-
 Rattus norvegicus ?
-
 ?
methylglyoxal + NADH
-
 Rattus norvegicus (R)-lactaldehyde + NAD+
-
 r
methylglyoxal + NADPH
-
 Rattus norvegicus lactaldehyde + NADP+
-
 ?
additional information specific for lactaldehyde Rattus norvegicus ?
-
 ?

pH Optimum

pH Optimum Minimum pH Optimum Maximum Comment Organism
11
-
 in the oxidation of D-lactaldehyde, increase of reaction rate up to pH 11 Rattus norvegicus

Cofactor

Cofactor Comment Organism Structure
NAD+
-
 Rattus norvegicus
NADH
-
 Rattus norvegicus