Crystallization (Comment) | Organism |
---|---|
in complex with ligands estradiol, equiline, 5-alpha-dihydrotestosterone, O5'-[9-(3,17beta-dihydroxy-1,3,5(10)-estratrien-16beta-yl)nonanoyl]adenosine and 3-[[(16beta,17beta)-3,17-dihydroxyestra-1,3,5(10)trien-16-yl]methyl]benzamide. Construction of pharmacophore model | Homo sapiens |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
(6-hydroxy-1,3-benzothiazol-2-yl)(3-hydroxyphenyl)methanone | modeling of binding to crystal structure shows five hydrogen bond interactions and a cation-pi-interaction | Homo sapiens | |
3-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide | modeling of binding to crystal structure shows five hydrogen bond interactions and a cation-pi-interaction | Homo sapiens |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
cytosol | - |
Homo sapiens | 5829 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Homo sapiens | P14061 | - |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
placenta | - |
Homo sapiens | - |
Synonyms | Comment | Organism |
---|---|---|
17beta-HSD1 | - |
Homo sapiens |
IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
---|---|---|---|---|---|
0.000044 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | (6-hydroxy-1,3-benzothiazol-2-yl)(3-hydroxyphenyl)methanone | |
0.000243 | - |
pH not specified in the publication, temperature not specified in the publication | Homo sapiens | 3-hydroxy-N-(6-hydroxy-1,3-benzothiazol-2-yl)benzamide |