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Literature summary for 1.1.1.56 extracted from

  • Dothie, J.M.; Giglio, J.R.; Moore, C.B.; Tayler, S.S.; Hartley, B.S.
    Ribitol dehydrogenase of Klebsiella aerogenes. Sequence and properties of wild-type and mutant strains (1985), Biochem. J., 230, 569-578.
    View publication on PubMedView publication on EuropePMC
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Protein Variants

Protein Variants Comment Organism
G196P mutant D, increased activity towards xylitol Klebsiella aerogenes

General Stability

General Stability Organism
half life in crude extract at 55°C mutant B: 6 min Klebsiella aerogenes
half life in crude extract at 55°C mutant D: 30 min Klebsiella aerogenes
half life in crude extract at 55°C wild type: 20 min Klebsiella aerogenes

Organism

Organism UniProt Comment Textmining
Klebsiella aerogenes
-
-
-

Purification (Commentary)

Purification (Comment) Organism
ribitol dehydrogenase A and B Klebsiella aerogenes

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
ribitol + NAD+
-
 Klebsiella aerogenes D-ribulose + NADH
-
 ?
xylitol + NAD+ mutants have increased xylitol activity Klebsiella aerogenes D-xylulose + NADH + H+
-
 ?

Synonyms

Synonyms Comment Organism
ribitol dehydrogenase A wild type Klebsiella aerogenes
ribitol dehydrogenase B mutant enzyme with different properties Klebsiella aerogenes
ribitol dehydrogenase D mutant enzyme with different properties Klebsiella aerogenes

Temperature Stability [°C]

Temperature Stability Minimum [°C] Temperature Stability Maximum [°C] Comment Organism
55
-
 half-life of mutant B is 6 min, half-life of mutant D is 30 min, half-life of wild-type enzyme is 20 min Klebsiella aerogenes