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Literature summary for 1.1.1.55 extracted from
- Enzymic conversion of lactaldehyde to propanediol (1960), J. Biol. Chem., 235, 1609-1612.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| cysteine | - |
Sus scrofa |  |
| Dimercaptopropanol | - |
Sus scrofa | |
| glutathione | - |
Sus scrofa | |
| p-chloromercuribenzoate | - |
Sus scrofa | |
| thioethanol | - |
Sus scrofa | |
KM Value [mM]
| KM Value [mM] | KM Value Maximum [mM] | Substrate | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 1.9 | - |
L-lactaldehyde | - |
Sus scrofa | |
Natural Substrates/ Products (Substrates)
| Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-lactaldehyde + NADPH + H+ | Spinacia oleracea | - |
propane-1,2-diol + NADP+ | - |
r | |
| L-lactaldehyde + NADPH + H+ | Pseudomonas aeruginosa | - |
propane-1,2-diol + NADP+ | - |
r | |
| L-lactaldehyde + NADPH + H+ | Sus scrofa | the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values | propane-1,2-diol + NADP+ | - |
r | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Pseudomonas aeruginosa | - |
- |
- |
| Spinacia oleracea | - |
- |
- |
| Sus scrofa | - |
- |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Sus scrofa |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| brain | - |
Sus scrofa | - |
| heart | - |
Sus scrofa | - |
| kidney | - |
Sus scrofa | - |
| leaf | - |
Spinacia oleracea | - |
| liver | - |
Sus scrofa | - |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| L-lactaldehyde + NADPH + H+ | - |
Spinacia oleracea | propane-1,2-diol + NADP+ | - |
r | |
| L-lactaldehyde + NADPH + H+ | - |
Pseudomonas aeruginosa | propane-1,2-diol + NADP+ | - |
r | |
| L-lactaldehyde + NADPH + H+ | the equilibrium greatly favors the reduction of L-lactaldehyde and can be reversed in the presence of high concentrations of propane-1,2-diol at high pH-values | Sus scrofa | propane-1,2-diol + NADP+ | - |
r | |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 7.4 | - |
- |
Sus scrofa |
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Release 2023.1 (January 2023)
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