Crystallization (Comment) | Organism |
---|---|
refined model, also with bound cortisone molecule | Streptomyces exfoliatus |
Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
---|---|---|---|
28000 | - |
4 * 28000, about, crystal structure and sequence analysis | Streptomyces exfoliatus |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
3alpha,20beta-hydroxysteroid androstanes or pregnane derivatives + NAD(P)H | Streptomyces exfoliatus | enzyme belongs to the group of short-chain dehydrogenases | ? | - |
r |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Streptomyces exfoliatus | - |
- |
- |
Reaction | Comment | Organism | Reaction ID |
---|---|---|---|
androstan-3alpha,17beta-diol + NAD+ = 17beta-hydroxyandrostan-3-one + NADH + H+ | deduced reaction mechanism from crystal structure model | Streptomyces exfoliatus |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
3alpha,20beta-hydroxysteroid androstanes or pregnane derivatives + NAD(P)H | enzyme belongs to the group of short-chain dehydrogenases | Streptomyces exfoliatus | ? | - |
r |
Subunits | Comment | Organism |
---|---|---|
tetramer | 4 * 28000, about, crystal structure and sequence analysis | Streptomyces exfoliatus |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Streptomyces exfoliatus |