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Literature summary for 1.1.1.50 extracted from

  • Lindemann, P.; Luckner, M.
    Biosynthesis of pregnane derivatives in somatic embryos of Digitalis lanata (1997), Phytochemistry, 46, 507-513.
No PubMed abstract available
Search for more literature for 1.1.1.50

Natural Substrates/ Products (Substrates)

Natural Substrates Organism Comment (Nat. Sub.) Natural Products Comment (Nat. Pro.) Rev. Reac.
5beta-pregnan-3,20-dione + NAD(P)H Digitalis lanata 3alpha-hydroxysteroid-5beta-oxidoreductase activity 3alpha-hydroxy-5beta-pregnan-20-one + NAD(P)+
-
 ?
5beta-pregnan-3,20-dione + NAD(P)H Digitalis lanata VIII 3alpha-hydroxysteroid-5beta-oxidoreductase activity 3alpha-hydroxy-5beta-pregnan-20-one + NAD(P)+
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 ?

Organism

Organism UniProt Comment Textmining
Digitalis lanata
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Source Tissue

Source Tissue Comment Organism Textmining
embryo somatic, dark-grown Digitalis lanata
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embryo preembryonic mass Digitalis lanata
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leaf illuminated or light grown leaves Digitalis lanata
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Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
2999 4199 green leaves Digitalis lanata

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
5beta-pregnan-3,20-dione + NAD(P)H 3alpha-hydroxysteroid-5beta-oxidoreductase activity Digitalis lanata 3alpha-hydroxy-5beta-pregnan-20-one + NAD(P)+
-
 ?
5beta-pregnan-3,20-dione + NAD(P)H 3alpha-hydroxysteroid-5beta-oxidoreductase activity Digitalis lanata VIII 3alpha-hydroxy-5beta-pregnan-20-one + NAD(P)+
-
 ?