Literature summary for 1.1.1.49 extracted from

Esposito, S.; Massaro, G.; Vona, V.; Di Martino Rigano, V.; Carfagna, S.
Glutamate synthesis in barley roots: the role of the plastidic glucose-6-phosphate dehydrogenase (2003), Planta, 216, 639-647.

Search for more literature for 1.1.1.49

Inhibitors

Inhibitors	Comment	Organism	Structure
NADPH	slight inhibition	Hordeum vulgare

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.009	-	NADP+	25°C	Hordeum vulgare
0.96	-	D-glucose 6-phosphate	25°C	Hordeum vulgare

Localization

Localization	Comment	Organism	GeneOntology No.	Textmining
plastid	isozyme, not in chloroplast	Hordeum vulgare	9536	-

Molecular Weight [Da]

Molecular Weight [Da]	Molecular Weight Maximum [Da]	Comment	Organism
53100	-	x * 53100, SDS-PAGE	Hordeum vulgare

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
D-glucose 6-phosphate + NADP+	Hordeum vulgare	involved in oxidative pentose phosphate pathway in roots, related to glutamate synthesis in the plastids	D-glucono-1,5-lactone 6-phosphate + NADPH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Hordeum vulgare	-	var. Alfeo, root plastidic isozyme	-

Purification (Commentary)

Purification (Comment)	Organism
rapid partial purifiation from root plastids, 17.7fold	Hordeum vulgare

Source Tissue

Source Tissue	Comment	Organism	Textmining
root	-	Hordeum vulgare	-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg]	Specific Activity Maximum [µmol/min/mg]	Comment	Organism
2.15	-	partially purified enzyme	Hordeum vulgare

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
D-glucose 6-phosphate + NADP+	-	Hordeum vulgare	D-glucono-1,5-lactone 6-phosphate + NADPH + H+	-	?
D-glucose 6-phosphate + NADP+	involved in oxidative pentose phosphate pathway in roots, related to glutamate synthesis in the plastids	Hordeum vulgare	D-glucono-1,5-lactone 6-phosphate + NADPH + H+	-	?

Subunits

Subunits	Comment	Organism
?	x * 53100, SDS-PAGE	Hordeum vulgare

Synonyms

Synonyms	Comment	Organism
Glc6PDH	-	Hordeum vulgare
glucose-6-phosphate dehydrogenase	-	Hordeum vulgare

Temperature Optimum [°C]

Temperature Optimum [°C]	Temperature Optimum Maximum [°C]	Comment	Organism
25	-	assay at	Hordeum vulgare

Cofactor

Cofactor	Comment	Organism	Structure
NADP+	-	Hordeum vulgare

Ki Value [mM]

Ki Value [mM]	Ki Value maximum [mM]	Inhibitor	Comment	Organism	Structure
0.059	-	NADPH	25°C	Hordeum vulgare

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Release 2023.1 (January 2023)