Literature summary for 1.1.1.44 extracted from

Jin, X.M.; Chang, Y.K.; Lee, J.H.; Hong, S.K.
Effects of increased NADPH concentration by metabolic engineering of the pentose phosphate pathway on antibiotic production and sporulation in Streptomyces lividans TK24 (2017), J. Microbiol. Biotechnol., 27, 1867-1876 .

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Cloned(Commentary)

Cloned (Comment)	Organism
6-phosphogluconate dehydrogenase (encoded by zwf3) is overexpressed with opc encoding a positive allosteric effector essential for Zwf activity in Streptomyces lividans TK24	Streptomyces lividans

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	Streptomyces lividans	-	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	?
6-phospho-D-gluconate + NADP+	Streptomyces lividans TK24	-	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	?

Organism

Organism	UniProt	Comment	Textmining
Streptomyces lividans	-	-	-
Streptomyces lividans TK24	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	-	Streptomyces lividans	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	?
6-phospho-D-gluconate + NADP+	-	Streptomyces lividans TK24	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	?

Synonyms

Synonyms	Comment	Organism
6-phosphogluconate dehydrogenase	-	Streptomyces lividans
6PGDH	-	Streptomyces lividans
zwf3	-	Streptomyces lividans

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Release 2023.1 (January 2023)