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Literature summary for 1.1.1.44 extracted from
- The effect of brimonidine and proparacaine on metabolic enzymes Glucose-6-phosphate dehydrogenase, 6-phosphogluconate dehydrogenase, and glutathione reductase (2022), Biotechnol. Appl. Biochem., 69, 281-288.
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| brimonidine | competitive inhibition | Homo sapiens |  |
| proparacaine | competitive inhibition | Homo sapiens | |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Homo sapiens | P52209 | - |
- |
Purification (Commentary)
| Purification (Comment) | Organism |
|---|---|
- |
Homo sapiens |
Source Tissue
| Source Tissue | Comment | Organism | Textmining |
|---|---|---|---|
| erythrocyte | - |
Homo sapiens | - |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| 6-phosphogluconate dehydrogenase | - |
Homo sapiens |
| 6PGD | - |
Homo sapiens |
Ki Value [mM]
| Ki Value [mM] | Ki Value maximum [mM] | Inhibitor | Comment | Organism | Structure |
|---|---|---|---|---|---|
| 0.066 | - |
brimonidine | pH and temperature not specified in the publication | Homo sapiens | |
| 0.811 | - |
proparacaine | pH and temperature not specified in the publication | Homo sapiens | |
IC50 Value
| IC50 Value | IC50 Value Maximum | Comment | Organism | Inhibitor | Structure |
|---|---|---|---|---|---|
| 0.109 | - |
pH and temperature not specified in the publication | Homo sapiens | brimonidine | |
| 0.602 | - |
pH and temperature not specified in the publication | Homo sapiens | proparacaine | |
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