Literature summary for 1.1.1.44 extracted from

Berdis, A.J.; Cook, P.F.
Chemical mechanism of 6-phosphogluconate dehydrogenase from Candida utilis from pH studies (1993), Biochemistry, 32, 2041-2046.

Search for more literature for 1.1.1.44

Activating Compound

Activating Compound	Comment	Organism	Structure
D-fructose 6-phosphate	slight activation	Cyberlindnera jadinii

Inhibitors

Inhibitors	Comment	Organism	Structure
6-phospho-D-allonate	-	Cyberlindnera jadinii
D-5-phosphoarabonate	-	Cyberlindnera jadinii
D-5-phosphoribonate	-	Cyberlindnera jadinii
D-6-sulfogluconate	-	Cyberlindnera jadinii
D-ribulose 5-phosphate	-	Cyberlindnera jadinii

KM Value [mM]

KM Value [mM]	KM Value Maximum [mM]	Substrate	Comment	Organism	Structure
0.22	-	6-phosphogluconate	-	Cyberlindnera jadinii

Natural Substrates/ Products (Substrates)

Natural Substrates	Organism	Comment (Nat. Sub.)	Natural Products	Comment (Nat. Pro.)	Rev.	Reac.
6-phospho-D-gluconate + NADP+	Cyberlindnera jadinii	-	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r

Organism

Organism	UniProt	Comment	Textmining
Cyberlindnera jadinii	-	-	-

Substrates and Products (Substrate)

Substrates	Comment Substrates	Organism	Products	Comment (Products)	Rev.	Reac.
2-deoxy-6-phosphogluconate + NADP+	-	Cyberlindnera jadinii	2-deoxy-3-oxo 6-phosphogluconate + NADPH	-	r
6-O-phosphono-D-mannonic acid + NADP+	-	Cyberlindnera jadinii	? + NADPH	-	?
6-phospho-D-gluconate + NADP+	-	Cyberlindnera jadinii	D-ribulose 5-phosphate + CO2 + NADPH + H+	-	r
ribulose 5-phosphate + H2O + NADPH	-	Cyberlindnera jadinii	?	-	?

pH Optimum

pH Optimum Minimum	pH Optimum Maximum	Comment	Organism
7.5	-	-	Cyberlindnera jadinii

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Release 2023.1 (January 2023)