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Literature summary for 1.1.1.431 extracted from

  • Rafiqul, I.S.; Sakinah, A.M.; Zularisam, A.W.
    Inhibition by toxic compounds in the hemicellulosic hydrolysates on the activity of xylose reductase from Candida tropicalis (2015), Biotechnol. Lett., 37, 191-196.
    View publication on PubMed
Search for more literature for 1.1.1.431

Inhibitors

Inhibitors Comment Organism Structure
5-hydroxymethylfurfural
-
 Candida tropicalis
acetic acid
-
 Candida tropicalis
furfural
-
 Candida tropicalis
Tannic acid
-
 Candida tropicalis

Organism

Organism UniProt Comment Textmining
Candida tropicalis
-
-
-
Candida tropicalis IFO 0618
-
-
-

Specific Activity [micromol/min/mg]

Specific Activity Minimum [µmol/min/mg] Specific Activity Maximum [µmol/min/mg] Comment Organism
11.16
-
 pH 7.0, 25°C Candida tropicalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
D-xylose + NADPH + H+
-
 Candida tropicalis xylitol + NADP+
-
 ?
D-xylose + NADPH + H+
-
 Candida tropicalis IFO 0618 xylitol + NADP+
-
 ?

Temperature Optimum [°C]

Temperature Optimum [°C] Temperature Optimum Maximum [°C] Comment Organism
25
-
-
 Candida tropicalis

Temperature Range [°C]

Temperature Minimum [°C] Temperature Maximum [°C] Comment Organism
40
-
 enzyme is fully active up to 40°C Candida tropicalis

Cofactor

Cofactor Comment Organism Structure
NADPH enzyme is specific for NADPH Candida tropicalis

IC50 Value

IC50 Value IC50 Value Maximum Comment Organism Inhibitor Structure
additional information
-
 IC50 value 0.4 g/l, pH 7.0, 25°C Candida tropicalis 5-hydroxymethylfurfural
additional information
-
 IC50 value 11 g/l, pH 7.0, 25°C Candida tropicalis acetic acid
additional information
-
 IC50 value 2.3 g/l, pH 7.0, 25°C Candida tropicalis furfural
additional information
-
 IC50 value 6.4 g/l, pH 7.0, 25°C Candida tropicalis Tannic acid