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Literature summary for 1.1.1.430 extracted from
- Systematic strain construction and process development: Xylitol production by Saccharomyces cerevisiae expressing Candida tenuis xylose reductase in wild-type or mutant form (2015), Biores. Technol., 198, 732-738.
Application
| Application | Comment | Organism |
|---|---|---|
| synthesis | expression of wild-type Xyl1 or an NADH-specific mutant in Saccharomyces cerevisiae. The Xyl1 mutant decreases the biocatalysts performance, suggesting use of the NADPH-preferring wild-type enzyme when (semi-)aerobic conditions are applied. In a bioreactor process, the best-performing strain converts 40 g/l xylose with an initial productivity of 1.16 g/l/h and a xylitol yield of 100% | Yamadazyma tenuis |
Protein Variants
| Protein Variants | Comment | Organism |
|---|---|---|
| K274R/N276D | NADH-specific mutant, Saccharomyces cerevisiae expressing mutant K274R/N276D exhibits intracellular activities of 0.94 U/mg 1.07 U/mg with NADPH and NADH, respectively | Yamadazyma tenuis |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Yamadazyma tenuis | O74237 | - |
- |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| XYL1 | - |
Yamadazyma tenuis |
Cofactor
| Cofactor | Comment | Organism | Structure |
|---|---|---|---|
| NADH | - |
Yamadazyma tenuis |  |
| NADPH | - |
Yamadazyma tenuis | |
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Release 2023.1 (January 2023)
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