Activating Compound | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Saccharomyces cerevisiae |
Protein Variants | Comment | Organism |
---|---|---|
K171L | mutant IDH1K171L | Saccharomyces cerevisiae |
Inhibitors | Comment | Organism | Structure |
---|---|---|---|
130-nucleotide transcript containing the 5'-untranslated regions of the yeast mitochondrial COX2 mRNA | inhibition with a 50% reduction in activity observed with 40 nM mRNA | Saccharomyces cerevisiae |
Localization | Comment | Organism | GeneOntology No. | Textmining |
---|---|---|---|---|
mitochondrion | - |
Saccharomyces cerevisiae | 5739 | - |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Saccharomyces cerevisiae | - |
- |
- |
Saccharomyces cerevisiae MMY011 | - |
- |
- |
Purification (Comment) | Organism |
---|---|
Ni2+-nitrilotriacetic acid superflow resin chromatography | Saccharomyces cerevisiae |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-isocitrate + NAD+ | - |
Saccharomyces cerevisiae | 2-oxoglutarate + CO2 + NADH | - |
ir | |
D-isocitrate + NAD+ | - |
Saccharomyces cerevisiae MMY011 | 2-oxoglutarate + CO2 + NADH | - |
ir |
Synonyms | Comment | Organism |
---|---|---|
IDH | - |
Saccharomyces cerevisiae |
NAD+-specific isocitrate dehydrogenase | - |
Saccharomyces cerevisiae |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Saccharomyces cerevisiae |