Protein Variants | Comment | Organism |
---|---|---|
additional information | generation of an antisense construct targeting the C4 isoform of NADP-malic enzyme, transformation of Flaveria bidentis via Agrobacterium tumefaciens, transgenic Flaveria bidentis plants exhibit a 34% to 75% reduction in NADP-ME activity relative to the wild-type with no visible growth phenotype. In transgenic plants, CO2 assimilation rates at high intercellular CO2 are significantly reduced, whereas the in vitro activities of both phosphoenolpyruvate carboxylase and Rubisco are increased | Flaveria bidentis |
Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NADP+ | Flaveria bidentis | - |
pyruvate + CO2 + NADPH | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Flaveria bidentis | - |
- |
- |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
bundle sheath cell | - |
Flaveria bidentis | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(S)-malate + NADP+ | - |
Flaveria bidentis | pyruvate + CO2 + NADPH | - |
? |
Synonyms | Comment | Organism |
---|---|---|
NADP-malic enzyme | - |
Flaveria bidentis |
NADP-ME | - |
Flaveria bidentis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NADP+ | - |
Flaveria bidentis |
General Information | Comment | Organism |
---|---|---|
malfunction | antisense reduction of NADP-ME alters C3-C4 cycle coordination. Increase in Rubisco and phosphoenolpyruvate carboxylase activity and leaf nitrogen in low-NADP-ME antisense plants | Flaveria bidentis |
physiological function | NADP-malic enzyme is the primary enzyme decarboxylating malate in bundle sheath cells to supply CO2 to Rubisco | Flaveria bidentis |