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Literature summary for 1.1.1.4 extracted from
- Purification and characterization of a (R)-2,3-butanediol dehydrogenase from Saccharomyces cerevisiae (1990), Arch. Microbiol., 154, 267-273.
Crystallization (Commentary)
| Crystallization (Comment) | Organism |
|---|---|
- |
Saccharomyces cerevisiae |
Inhibitors
| Inhibitors | Comment | Organism | Structure |
|---|---|---|---|
| dipicolinate | - |
Saccharomyces cerevisiae |  |
| EDTA | - |
Saccharomyces cerevisiae | |
| o-phenanthroline | - |
Saccharomyces cerevisiae | |
Metals/Ions
| Metals/Ions | Comment | Organism | Structure |
|---|---|---|---|
| Mg2+ | activation | Saccharomyces cerevisiae | |
| Mn2+ | activation | Saccharomyces cerevisiae | |
Molecular Weight [Da]
| Molecular Weight [Da] | Molecular Weight Maximum [Da] | Comment | Organism |
|---|---|---|---|
| 35000 | - |
4 * 35000, SDS-PAGE | Saccharomyces cerevisiae |
| 140000 | - |
gel filtration | Saccharomyces cerevisiae |
Organism
| Organism | UniProt | Comment | Textmining |
|---|---|---|---|
| Saccharomyces cerevisiae | - |
- |
- |
Substrates and Products (Substrate)
| Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
|---|---|---|---|---|---|---|
| (R,S)-3-hydroxy-2-pentanone + NADH | - |
Saccharomyces cerevisiae | 2,3-pentanediol + NAD+ | - |
r | |
| (R,S)-4-hydroxy-3-pentanone + NADH | - |
Saccharomyces cerevisiae | 2,3-pentanediol + NAD+ | - |
r | |
| 1,2-butanediol + NAD+ | - |
Saccharomyces cerevisiae | ? | - |
? | |
| 1,2-propanediol + NAD+ | - |
Saccharomyces cerevisiae | ? | - |
? | |
| 1-hydroxy-2-butanone + NADH | - |
Saccharomyces cerevisiae | ? | - |
? | |
| 2,3-butanediol + NAD+ | 2,3-butanediol without specification of stereochemistry | Saccharomyces cerevisiae | acetoin + NADH | - |
r | |
| 2,3-butanediol + NAD+ | oxidation occurs selectively at the (R)-center of 2,3-butanediol | Saccharomyces cerevisiae | acetoin + NADH | - |
r | |
| 2,3-pentanediol + NAD+ | racemate | Saccharomyces cerevisiae | 4-hydroxy-3-pentanone + 3-hydroxy-2-pentanone + NADH | - |
r | |
| acetoin + NADH + H+ | - |
Saccharomyces cerevisiae | 2,3-butanediol + NAD+ | - |
r | |
| diacetyl + NADH | - |
Saccharomyces cerevisiae | 2,3-butanediol + NAD+ | - |
? | |
| hydroxyacetone + NADH | - |
Saccharomyces cerevisiae | 1,2-propanediol | - |
? | |
Subunits
| Subunits | Comment | Organism |
|---|---|---|
| tetramer | 4 * 35000, SDS-PAGE | Saccharomyces cerevisiae |
Synonyms
| Synonyms | Comment | Organism |
|---|---|---|
| (R)-2,3-butanediol dehydrogenase | - |
Saccharomyces cerevisiae |
pH Optimum
| pH Optimum Minimum | pH Optimum Maximum | Comment | Organism |
|---|---|---|---|
| 6.7 | - |
substrate reduction | Saccharomyces cerevisiae |
| 7.2 | - |
substrate oxidation | Saccharomyces cerevisiae |
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Release 2023.1 (January 2023)
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