Cloned (Comment) | Organism |
---|---|
expression in Escherichia coli | Bacillus subtilis |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Bacillus subtilis | - |
- |
- |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
D-glucose + NAD+ | poor substrate | Bacillus subtilis | 3-dehydro-D-glucose + NADH + H+ | - |
? | |
D-glucose 6-phosphate + NAD+ | - |
Bacillus subtilis | 3-dehydro-D-glucose 6-phosphate + NADH + H+ | - |
? | |
inositol + NAD+ | poor substrate | Bacillus subtilis | ? + NADH + H+ | - |
? | |
additional information | no substrate: UDP-glucose | Bacillus subtilis | ? | - |
? |
Synonyms | Comment | Organism |
---|---|---|
ntdC | - |
Bacillus subtilis |
yhjJ | - |
Bacillus subtilis |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
additional information | no cofactor: NADP+ | Bacillus subtilis | |
NAD+ | highly specific | Bacillus subtilis |
General Information | Comment | Organism |
---|---|---|
physiological function | the ntd operon is essential for biosynthesis of the unusual disaccharide 3,3'-neotrehalosadiamine. The enzymes catalyze the biosynthesis of kanosamine from D-glucose 6-phosphate. NtdC is a D-glucose-6-phosphate-3-dehydrogenase, NtdA is a pyridoxal phosphate-dependent 3-oxo-glucose-6-phosphate:glutamate aminotransferase, and NtdB is a kanosamine-6-phosphate phosphatase | Bacillus subtilis |