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Literature summary for 1.1.1.36 extracted from

  • Ylianttila, M.S.; Pursiainen, N.V.; Haapalainen, A.M.; Juffer, A.H.; Poirier, Y.; Kalervo Hiltunen, J.; Glumoff, T.
    Crystal structure of yeast peroxisomal multifunctional enzyme: structural basis for substrate specificity of (3R)-hydroxyacyl-CoA dehydrogenase units (2006), J. Mol. Biol., 358, 1286-1295.
    View publication on PubMed
Search for more literature for 1.1.1.36

Cloned(Commentary)

Cloned (Comment) Organism
expressed in Escherichia coli Candida tropicalis

Crystallization (Commentary)

Crystallization (Comment) Organism
hanging-drop vapour diffusion Candida tropicalis

Localization

Localization Comment Organism GeneOntology No. Textmining

Organism

Organism UniProt Comment Textmining
Candida tropicalis
-
-
-

Purification (Commentary)

Purification (Comment) Organism
Resource S cation exchange chromatography and Superdex 200 HR 10/30 column chromatography Candida tropicalis

Substrates and Products (Substrate)

Substrates Comment Substrates Organism Products Comment (Products) Rev. Reac.
(3R)-hydroxybutyryl-CoA + NAD+
-
 Candida tropicalis 3-oxobutylryl-CoA + NADH
-
 ?
(3R)-hydroxydecanoyl-CoA + NAD+
-
 Candida tropicalis 3-oxodecanoyl-CoA + NADH
-
 ?
acetoacetyl-CoA + NADH + H+
-
 Candida tropicalis L-3-hydroxybutyryl-CoA + NAD+
-
 ?

Subunits

Subunits Comment Organism
heterodimer residues 1-313 and 314-604 forming the dehydrogenase A and B units, respectively Candida tropicalis

Synonyms

Synonyms Comment Organism
(3R)-hydroxyacyl-CoA dehydrogenase
-
 Candida tropicalis