Natural Substrates | Organism | Comment (Nat. Sub.) | Natural Products | Comment (Nat. Pro.) | Rev. | Reac. |
---|---|---|---|---|---|---|
(-)-secoisolariciresinol + 2 NAD+ | Forsythia x intermedia | - |
(-)-matairesinol + 2 NADH + 2 H+ | - |
? |
Organism | UniProt | Comment | Textmining |
---|---|---|---|
Forsythia x intermedia | Q94KL7 | Forsythia suspensa x Forsythia viridissima | - |
Source Tissue | Comment | Organism | Textmining |
---|---|---|---|
leaf | seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, analysis of gene expression profile of secoisolariciresinol dehydrogenase (SIRD) and other related enzymes in the leaves of Forsythia suspense from April to November. The SIRD expression is prominent from April to May, not detected in June to July, and then increases again from September to November. All of the lignans in the leaf continuously increase from April to June, reach the maximal level in June, and then decrease | Forsythia x intermedia | - |
Substrates | Comment Substrates | Organism | Products | Comment (Products) | Rev. | Reac. |
---|---|---|---|---|---|---|
(-)-secoisolariciresinol + 2 NAD+ | - |
Forsythia x intermedia | (-)-matairesinol + 2 NADH + 2 H+ | - |
? |
Synonyms | Comment | Organism |
---|---|---|
SirD | - |
Forsythia x intermedia |
Cofactor | Comment | Organism | Structure |
---|---|---|---|
NAD+ | - |
Forsythia x intermedia |
General Information | Comment | Organism |
---|---|---|
metabolism | the enzyme is involved in the lignan biosynthetic pathways in Forsythia, overview | Forsythia x intermedia |
physiological function | the enzyme SIRD is involved in the biosynthesis of lignan matairesinol in Forsythia. The leaves show seasonal alteration in amounts of major lignans, such as pinoresinol, matairesinol, and arctigenin, gene expression profile of secoisolariciresinol dehydrogenase (SIRD) and other related enzymes in the leaves of Forsythia suspense from April to November: all of the lignans in the leaf continuously increase from April to June, reach the maximal level in June, and then decrease | Forsythia x intermedia |